KARVIAH Sub-study: Examining the use of curcumin on cognition and mood in an older populatio

Phase 2

• Conditions: Alzheimer's disease; depression; Neurological - Alzheimer's disease; Mental Health - Depression

• Registration Number: ACTRN12616001113448
• Lead Sponsor: Macquarie University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-08-17
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Participant within the KARVIAH study - ACTRN 12613000681752
Cognitively healthy participants, as determined by the MoCA score.
Able to undertake a computerised battery
No evidence of depression
Male or female
(full inclusion as per main study)

Exclusion Criteria

Diagnosis of dementia based on the revised criteria from NIA / AA
or evidence of cognitive decline suggesting MCI
Evidence of depression based on the DASS
(full exclusion as per main study)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Attention tasks as measured using a computerised cognitive battery (CogState)[Baseline (0) prior to IP administration; 1 hour post dose; and 3 hours post dose. ];Working memory as measured using a computerised cognitive battery (CogState)[Baseline (0) prior to IP administration, 1 hour post dose and 3 hours post dose.]

Secondary Outcome Measures

Name	Time	Method
Mood as measured using the depression and anxiety sub scale (DASS)[Baseline (0) prior to IP administration; and 3 hours post dose];Anxiety as measured using the depression and anxiety sub scale (DASS)[Baseline (0) prior to IP administration and 3 hours post dose]