Performance of the Osteoporosis Self-Assessment Tool (OST) and Osteoporosis Risk Assessment Index (ORAI) in Predicting Osteoporosis in Postmenopausal Turkish Women
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 1,500
- 主要终点
- Dual-energy X-ray absorptiometry (DEXA)
研究概览
简要总结
The aim of this study is to compare the Osteoporosis Risk Assessment Tool and the Osteoporosis Self-Assessment Tool with the gold standard DEXA in determining the risk of osteoporosis in the lumbar and femoral regions in female individuals in the Turkish population, and to investigate their sensitivity and specificity in the first stage of screening for the detection of female osteoporosis.
详细描述
This study will be conducted as a single-center, retrospective study at the Physical Medicine and Rehabilitation Clinic of Kayseri City Hospital between January 2024 and January 2025. This study will include female patients aged 50-75 who underwent osteoporosis screening with DEXA at the Kayseri City Hospital FTR outpatient clinics between January 2021 and January 2024. Patient data will be obtained retrospectively from the hospital database. Sociodemographic data (age, height, weight, body mass index) and current laboratory data (complete blood count, biochemical values (fasting blood sugar, BUN, creatinine, AST, ALT, calcium, phosphorus, alkaline phosphatase, total protein, albumin, parathyroid hormone, vitamin D3, T4, TSH), and DEXA values (bone mineral density, lumbar vertebrae, and femoral neck and total femur T scores) will be recorded. The OST score will be calculated using body weight and age parameters. The ORAI score will be calculated using age, weight, and estrogen use from hospital data.
The data will be evaluated using the SPSS 24.0 software package. Descriptive statistical analyses will include calculations of mean, standard deviation, frequency, and percentages. In comparative statistics, the Student T-test or Mann Whitney U-test will be used to compare independent groups. Chi-square analysis will be applied to compare categorical variables. Pearson or Spearman correlation analyses will be applied to evaluate the relationship between variables. Both groups will be compared, and p<0.05 will be considered statistically significant.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 50 Years 至 75 Years(Adult, Older Adult)
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Postmenopausal women aged 50-75
- •Patients who underwent imaging with the STRATOS DEXA device at Kayseri City Hospital
排除标准
- •Patients younger than 50 or older than 75 years of age
- •Patients with secondary osteoporosis
- •Male patients
- •Patients with uncontrolled severe comorbid conditions
- •Patients with a history of pathological fractures
研究组 & 干预措施
female osteoporosis group
结局指标
主要结局
Dual-energy X-ray absorptiometry (DEXA)
时间窗: January 2021 - January 2024
Dual-energy X-ray absorptiometry (DEXA)
Osteoporosis Self-Assessment Tool (OST)
时间窗: January 2021 - January 2024
Osteoporosis Self-Assessment Tool (OST)
Osteoporosis Risk Assessment Index (ORAI)
时间窗: January 2021 - January 2024
Osteoporosis Risk Assessment Index (ORAI)
次要结局
未报告次要终点
研究者
Fatma Gül Ülkü Demir
MD
Kayseri City Hospital
