Mechanisms of acupuncture intervention on amnesia-type mild cognitive impairment based on large-scale network related to episodic memory
- Conditions
- Amnesia-type mild cognitive impairment
- Registration Number
- ITMCTR2000003326
- Lead Sponsor
- Shenzhen Bao'an District People's Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
1. Subjects meeting the diagnostic criteria of aMCI;
2. Subjects aged 55-70 years;
3. Subjects with middle school education or above;
4. The objects who have been proved to be healthy by physical examination in the third grade a hospital in the past half a year;
5. Subjects with body mass index (BMI) in the range of 20-24;
6. All of them are right handed;
7. Subjects participated voluntarily and signed informed consent.
1. Objects with metal residues and tattoos in the body;
2. Objects who are afraid of MRI or can not be scanned by MRI for other reasons;
3. Objects with or suspected brain lesions;
4. The object of heavy drinking and drug abuse;
5. Patients with mental history or congenital mental retardation; patients who are taking anti anxiety or anti depression drugs and receiving psychological treatment in the past 3 months;
6. Patients with serious heart, liver and kidney diseases;
7. Patients with other diseases of the nervous system that can cause cognitive dysfunction, such as brain tumor, encephalitis, epilepsy, Parkinson's disease, etc.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Functional magnetic resonance data;Episodic memory scores before and after intervention;
- Secondary Outcome Measures
Name Time Method Safety indicators;Activity of daily living;Overall cognitive function;