Acute optic neuritis study: a monocentric, prospective observational study on symptomatology, diagnosis, therapy and prognosis of acute optic neuritis.

Recruiting

• Conditions: H46; G35; G36.0; Optic neuritis; Multiple sclerosis; Neuromyelitis optica [Devic]

• Registration Number: DRKS00027095
• Lead Sponsor: Experimental and Clinical Research Center (ECRC), AG Klinische Neuroimmunologie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-11-09
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 230

Inclusion Criteria

Diagnosis of acute optic neuritis
- 18 years and older
- Person capable of giving consent
- Person has health insurance (for clarification of possible incidental findings)
- Written consent to participate in the present study

Exclusion Criteria

Pregnancy at study inclusion, Relevant concomitant condition considered limiting to study feasibility (e.g., reduced general health due to comorbidities, obesity per magna, acute need for treatment for mental illness, dementia-related syndrome), Insufficient ability to cooperate

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The aim of the data collection is a prospective follow-up of patients with acute optic neuritis.

Secondary Outcome Measures

Name	Time	Method
Descriptive characterization of acute optic neuritis of different etiology and its course during the observation period, both at the level of structural tissue changes, at the level of immunological functions, at the level of symptoms and function, and at the level of subjective effects and possible modifiers of disease progression.