MedPath

Integrating Caregiver Support Into MS Care

Not Applicable
Completed
Conditions
Multiple Sclerosis
Interventions
Behavioral: Behavioral
Registration Number
NCT02835677
Lead Sponsor
VA Office of Research and Development
Brief Summary

With loss of mobility in multiple sclerosis (MS) comes an increase in amount and types of caregiver assistance, with a concomitant increase in burden for the caregiver. In fact, effect on caregiver burden can be seen as a potential indicator of the efficacy of MS management, suggesting that the caregiver is an appropriate and independent target for MS therapeutic strategies.

MS patients report difficulty implementing and continuing with home exercise, mobility, and walking programs. This feasibility study will test integration of a successful behavioral caregiving intervention into clinical practice to improve functioning of Veterans with multiple sclerosis (MS) and their Caregivers. Caregivers of Veterans with MS will receive a behavioral caregiver intervention designed to address caregiver coping and management of patient concerns, with special focus on patient mobility and walking. A pre-post intervention design will compare outcomes for Veterans and Caregivers.

For Veterans, the intervention will target Caregiver participation in home-based Veteran mobility activities. MS Caregivers report high burden, stress, and depression involved in caring for their loved ones, especially as mobility declines and these outcomes are related to physical and emotional health status of the patient. For Caregivers, the intervention will focus on improving Caregiver coping and on managing MS-related problems. Outcomes for both will be measured at baseline, 3 months, and 6 months.

Study Objectives include:

* Test whether a caregiver intervention can be integrated into an MS clinical setting.

* Determine whether Caregiver outcomes are improved (depression, burden, anxiety, and number of Veteran MS problems and safety alerts reported).

* Determine whether Veteran outcomes are improved (Expanded Disability Status Scale, timed up and go test, self-efficacy, and depression).

* Determine which types of Caregivers will benefit most.

* Determine which types of Veterans will benefit most.

* Refine materials for future clinical research, translation and implementation.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
25
Inclusion Criteria
  • Veteran being seen in MS clinic at Memphis VA
  • Veteran ambulatory
  • Caregiver/care partner who agrees to participate
Read More
Exclusion Criteria
  • None
Read More

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
InterventionBehavioralBehavioral intervention with caregivers to reduce stress and management of patient concerns, particularly ambulation
Primary Outcome Measures
NameTimeMethod
Number of Patient MS Problemsbaseline, 6 months

Caregiver primary outcome - number of possible troubling patient problems and concerns, range 0-27, lower better

Depression Measured With the Patient Health Questionnaire 9 (PHQ-9) Scalebaseline, 6 months

Caregiver primary outcome. PHQ-9, range 0-27, lower better

Burden Measured With the Zarit Burden Inventorybaseline, 6 months

Caregiver primary outcome. Zarit Burden Inventory, 12 item, 0-48, lower better

Anxiety Measured With the Generalized Anxiety Disorders 7 Scalebaseline, 6 months

Caregiver primary outcome. General Anxiety Disorders Scale - GAD-7, range 0-21, lower better

Bother With Patient MS ProblemsBaseline, 6 months

Number of troubling patient problems or concerns that bother the caregiver, range 0-27, lower better

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Memphis VA Medical Center, Memphis, TN

🇺🇸

Memphis, Tennessee, United States

© Copyright 2025. All Rights Reserved by MedPath