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Clinical Trials/NL-OMON52322
NL-OMON52322
Recruiting
N/A

Cardiac Imaging in congenital aortic stenosis: unravelling risk factors and predicting clinical outcome - CAS

Overview

Phase
N/A
Intervention
Not specified
Conditions
Not specified
Sponsor
Erasmus MC, Universitair Medisch Centrum Rotterdam
Enrollment
100
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
2 years ago
Study Type
Observational invasive

Investigators

Eligibility Criteria

Inclusion Criteria

  • The study population consists of 100 adult ConAoS patients, who are visiting
  • the outpatient clinic of the Erasmus MC.
  • In order to be eligible to participate in this study, a subject must meet the
  • following criteria:
  • Aged \>\= 18 years
  • Capable of understanding and signing informed consent.
  • Inclusion criteria for the CAS study are patients diagnosed with a valvular
  • congenital aortic stenosis. Two groups of patients will be included:
  • Patients with a prior aortic valve replacement (AVR)
  • Patients without a prior AVR and with an aortic jet velocity \>\= 2\.5 m/s.

Exclusion Criteria

  • A potential subject who meets any of the following criteria will be excluded
  • from participation in this study:
  • Patients with severe aortic regurgitation
  • Presence of any of the following contra\-indications for MRI
  • o Contra\-indication to gadolinium based contrast media (eGFR \<30
  • ml/min or contrast allergy)
  • o Other contra\-indications such as presence of pacemaker/ICD, severe
  • claustrophobia or pregnancy
  • Patients known with or previously treated because of significant aortic
  • coarctation.

Outcomes

Primary Outcomes

Not specified

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