Evaluation the effect of jujube and lemon balm extracts in patients with chronic obstructive pulmonary disease

Phase 3

Recruiting

Conditions: Chronic Obstructive Pulmonary Disease.
Chronic obstructive pulmonary disease, unspecified
j44.9

Registration Number: IRCT20220628055302N1

Lead Sponsor: Mashhad University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 60

Inclusion Criteria

People aged 40 to 70 with COPD, whose disease has been confirmed by a lung specialist
COPD patients who did not have a known anxiety disorder and were not under standard psychiatric treatment, but had a score of 8 or higher based on the HADS questionnaire
People who are satisfied with traditional treatment

Exclusion Criteria

Pregnancy and breastfeeding
A history of severe anxiety that requires classical medical treatment
People who are under the supervision of a psychiatrist or take psychiatric medication due to a known anxiety or mood disorder
People who have severe anxiety in the screening tests will be referred to a psychiatrist for diagnostic evaluation and standard treatment
Suffering from other medical diseases including hypothyroidism

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Anxiety score in HADS anxiety subscale questionnaire. Timepoint: At the beginning of the study (before the intervention) and the 3rd and 6th week. Method of measurement: HADS anxiety subscale questionnaire.;Anxiety score in Spielberger's Clear and Hidden Anxiety Questionnaire (STAI). Timepoint: At the beginning of the study (before the intervention) and the 3rd and 6th week. Method of measurement: Spielberger state anxiety questionnaire.;CAT score. Timepoint: At the beginning of the study (before the intervention) and the 3rd and 6th week. Method of measurement: CAT test.

Secondary Outcome Measures

Name	Time	Method
Distance traveled in the 6MWT. Timepoint: At the beginning of the study (before the intervention) and the 3rd and 6th. Method of measurement: 6-minute walk test (6MWT).;Number of times sitting and getting up in the chair. Timepoint: At the beginning of the study (before the intervention) and the 3rd and 6th. Method of measurement: 1-min sit-to-stand test (STST).;Blood oxygen saturation (SaO2). Timepoint: At the beginning and end of each round of the (STST) and (6MWT). Method of measurement: Pulse oximeter device.;Pulse rate. Timepoint: At the beginning and end of each round of the (STST) and (6MWT). Method of measurement: Pulse oximeter device.;Quality of Life score on WHO Quality of Life Questionnaire (Bref-WHOQol). Timepoint: Before and after intervention. Method of measurement: WHO Quality of Life Questionnaire.