Inhalation Intervention for Nausea in the Emergency Department
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 80
- 试验地点
- 2
- 主要终点
- Nausea Verbal Numerical Rating Scale (0-10) at 10 Minutes Post Intervention
研究概览
简要总结
Randomized controlled trial comparing inhalation of isopropyl alcohol vs placebo (normal saline) pads to treat nausea in emergency department patients.
详细描述
This study is to investigate if inhaling the scent of a typical medical alcohol prep pad will alleviate nausea as compared to a identically packaged normal saline prep pad for the Emergency Department patient with nausea. The study length will be 10 minutes long. The subjects will take several deep nasal inhalations at the 0, 2, 5 minute marks. Level of nausea will be recorded during these times and at 10 minutes. The investigators will also assess satisfaction of the intervention. As in previous post operative unit studies,the hypothesis is that there will a significant difference in levels of nausea between the alcohol pad group versus the normal saline pad group.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age range of 18-65 years of age
- •complaint of nausea and or vomiting
- •ability to breathe through nose
- •ability to read and write English
排除标准
- •allergy to isopropyl alcohol
- •pregnancy or pregnancy status unknown to subject. Pregnancy test only if part of clinical course.
- •recent upper respiratory infection
- •recent intake of cefoperazone, disulfiram, or metronidazole or any other medications that are known produce nausea when exposed to alcohol.
- •use of antiemetic or psychoactive drug within 24 hours
- •alcohol abuse
- •nicotine within last 4 hrs
结局指标
主要结局
Nausea Verbal Numerical Rating Scale (0-10) at 10 Minutes Post Intervention
时间窗: 10 minutes post intervention
Primary outcome is nausea and vomiting measured on a scale from 0 ("no nausea") to 10 ("worst nausea imaginable") Verbal Numerical Response Scale (VNRS) at 10 minutes post intervention.
次要结局
- Verbal Numerical Rating Scale Pain Score (0-10) at 10 Minutes Post Intervention(10 minutes post intervention)
研究者
Michael D. April
Residency Associate Program Director for Research
Brooke Army Medical Center