NCT06379412招募中不适用
A Cross-sectional Study on the Association of Peptidoglycan Fragments Derived From Gut Microbiota With Colorectal Cancer
Zhujiang Hospital1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2023年7月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- HPLC-MS/MS was used to detect peptidoglycan fragment content in biological specimens of 200 participants
研究概览
简要总结
The goal of this observational study is to explore the association of peptidoglycan fragments derived from gut microbiota with colorectal cancer (CRC). The main question it aims to answer is: Are peptidoglycan fragments from the gut microbiota associated with the progression of colorectal cancer? Participants will provide biological specimens (blood, feces, colon tissue obtained during surgery)
详细描述
To explore whether peptidoglycan fragments can be used as screening or diagnostic indicators for colorectal cancer
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •People who underwent total colonoscopy in gastroenteroscopy room.
- •People who agree to participate in this study and are willing to sign informed consent.
排除标准
- •Previous diagnosis of malignant tumors other than colorectal cancer.
- •Received any of the following drug treatments within 1 month before sample collection: ① Drugs used for the treatment of colorectal diseases; ② Antibiotics; ③probiotics; ④ Laxatives.
- •Patients with a family history of colorectal cancer.
结局指标
主要结局
HPLC-MS/MS was used to detect peptidoglycan fragment content in biological specimens of 200 participants
时间窗: baseline (before treatment)
The content of peptidoglycan fragments was detected by HPLC-MS/MS
次要结局
未报告次要终点
研究者
研究点 (1)
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