A clinical trial to evaluate the effectiveness of Amukkara chooranam and aya chenduram in the management of aan maladu (oligozoospermia) - A pilot study
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- changes in the semen parameter after the medication
研究概览
简要总结
Infertility is defined as the ability to achieve pregnancy after 12 months of regular unprotected intercourse, affects upto 15% of couple worldwide. Male factor solely contributes in about 20% of infertility couples or acting in conjugation with female fertility factor in 30% of infertility couples. Oligozoospermia refers specifically to the condition in which sperm concentration below the lower reference limit of 15 million sperm/mL of ejaculate. Oligozoospermia can be further classified as mild (between 10-15 million sperms/mL),moderate (between 5-10 million sperms/mL) and severe ( less than 5 million sperms/mL). According to Siddha Scholar Yugi muni symptoms like semen showing lack of sweetness, floating on water, absence of vitality & frothy micturation indicates Aan maladu [male infertility]. In Siddha, Thathu nashtam [Oligozoospermia] has not been described as a separate disease entity. There is no direct reference for the comparison of Thathu nashtam to oligozoospermia however its feature can be understood on the basis of the indirect references available in the Siddha literatures. The various nomenclature used in siddha texts in relation with Sukkilam the seventh udal thathu [physical constituent] can be compared to sperm and not semen alone since its function is reproducion. The term Thathu Rogam [vinthu vai patria 4 noi] denotes disease relating to sperm and Thathu kuraivu / Thathu pushti kuraivu denotes Oligozoospermia and hence the term Thathu nashtam can be compared to oligozoospermia of contemporary science as both are similar in terminology [oligo-low; zoospermia-spermatozoa in semen ; thathu – sperm; nashtam-lack, be deficient in].
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 22.00 Year(s) 至 45.00 Year(s)(—)
- 性别
- Male
入选标准
- •1.Male infertile patients with age between 22-45 years.
排除标准
- •1,Azoospermia-complete absence of sperm in the ejaculate
- •Aspermia-complete lack of semen
- •Necrospermia- spermatozoa in semen are dead
- •History of undescended testis
- •Inguinal hernia on physical examination.
结局指标
主要结局
changes in the semen parameter after the medication
时间窗: At baseline and after 3 months
次要结局
未报告次要终点
研究者
S ESWARI
National Institute of Siddha
