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临床试验/CTRI/2024/04/065757
CTRI/2024/04/065757尚未招募2 期

A clinical trial to evaluate the effectiveness of Amukkara chooranam and aya chenduram in the management of aan maladu (oligozoospermia) - A pilot study

DrSESWARI1 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2024年5月1日最近更新:

试验速览

阶段
2 期
状态
尚未招募
发起方
入组人数
10
试验地点
1
主要终点
changes in the semen parameter after the medication

研究概览

简要总结

Infertility is defined as the ability to achieve pregnancy after 12 months of regular unprotected intercourse, affects upto 15% of couple worldwide. Male factor solely contributes in about 20% of infertility couples or acting in conjugation with female fertility factor in 30% of infertility couples. Oligozoospermia refers specifically to the condition in which sperm concentration below the lower reference limit of 15 million sperm/mL of ejaculate. Oligozoospermia can be further classified as mild (between 10-15 million sperms/mL),moderate (between 5-10 million sperms/mL) and severe ( less than 5 million sperms/mL). According to Siddha Scholar Yugi muni symptoms like semen showing lack of sweetness, floating on water, absence of vitality & frothy micturation indicates Aan maladu [male infertility]. In Siddha, Thathu nashtam [Oligozoospermia] has not been described as a separate disease entity. There is no direct reference for the comparison of Thathu nashtam to oligozoospermia however its feature can be understood on the basis of the indirect references available in the Siddha literatures. The various nomenclature used in siddha texts in relation with Sukkilam the seventh udal thathu [physical constituent] can be compared to sperm and not semen alone since its function is reproducion. The term Thathu Rogam [vinthu vai patria 4 noi] denotes disease relating to sperm and Thathu kuraivu / Thathu pushti kuraivu denotes Oligozoospermia and hence the term Thathu nashtam can be compared to oligozoospermia of contemporary science as both are similar in terminology [oligo-low; zoospermia-spermatozoa in semen ; thathu – sperm; nashtam-lack, be deficient in].

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
22.00 Year(s) 至 45.00 Year(s)(—)
性别
Male

入选标准

  • 1.Male infertile patients with age between 22-45 years.

排除标准

  • 1,Azoospermia-complete absence of sperm in the ejaculate
  • Aspermia-complete lack of semen
  • Necrospermia- spermatozoa in semen are dead
  • History of undescended testis
  • Inguinal hernia on physical examination.

结局指标

主要结局

changes in the semen parameter after the medication

时间窗: At baseline and after 3 months

次要结局

未报告次要终点

研究者

发起方
DrSESWARI
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

S ESWARI

National Institute of Siddha

研究点 (1)

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