Effect of Pentoxifylline in improvement Myocardial Injury in Patients with ST-elevation myocardial infarction treated by primary percutaneous coronary interventio

Phase 3

Recruiting

• Conditions: Myocardial infarction.; ST elevation (STEMI) myocardial infarction of unspecified site; I21.3

• Registration Number: IRCT20240323061353N1
• Lead Sponsor: Bagheiat-allah University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 22 July 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

Diagnosis of STEMI, as chest pain lasting more than 30 minutes and less than 12 hours with ST-segment elevation at the J point on the ECG for more than 1 mm in at least two consecutive leads
Precancerous coronary intervention successful
sinus rhythm
Informed consent to participate in the study

Exclusion Criteria

Recent history (within 3 months) of coronary artery bypass grafting
Receive thrombolytic therapy
Recent electrophysiological interventions of the heart
Cardiogenic shock at the time of presentation
History of kidney failure (Creatinine > 2.5 mg/dL)
Allergy and contraindication to aspirin, clopidogrel or pentoxifylline
Those who are pregnant or breastfeeding
Dissatisfaction and those who want to stop the study at any time

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Troponion I. Timepoint: Upon entering the emergency room and then 8, 16 and 32 hours after revascularization treatment. Method of measurement: Blood test.;Interleukin 6. Timepoint: On arrival in the emergency room and 48 hours and 15 days after revascularization treatment. Method of measurement: Blood Test.;Hs-CRP. Timepoint: On arrival in the emergency room and 48 hours and 15 days after revascularization treatment. Method of measurement: Blood test.;CPK. Timepoint: On arrival to the emergency department as a baseline sample and every 8 hours to 48 hours after revascularization treatment. Method of measurement: Blood test.