7 Year Follow up Analysis on the Speed of Progression of Tooth Wear Using 3D Subtraction

Completed

• Conditions: Reflux Acid; Tooth Wear; Bruxism

• Registration Number: NCT04790110
• Lead Sponsor: Radboud University Medical Center

Brief Summary

Prospective observational study with 7-year follow up. 55 patients are included with moderate to severe tooth wear, whereby through informed consent the decision was taking to monitor the patients. At the baseline and 1, 3 5, and the 7-year recall digital 3D scans will be made, which will be compared and subtracted.

Detailed Description

Prospective observational study with 7-year follow up. 55 patients are included with moderate to severe tooth wear, whereby through informed consent the decision was taking to monitor the patients. At the baseline and the 5-year recall digital 3D scans will be made, which will be compared and subtracted. Per tooth the loss of material is measured in maximum loss in height (µm) and volume (mm3) per year, using best fit alignment and 3D subtraction.

The loss of tooth material will be analyzed using descriptive statistics and possible effects of jaw type, tooth type and cusp type will be analyzed using multi level regression models.

The use of index teeth will be analyzed.

Study Timeline

• Study Start: 2011-03-03
• Study First Submitted: 2021-02-09
• Study First Submitted QC: 2021-03-08
• Study First Posted: 2021-03-10
• Primary Completion: 2022-05-21
• Study Completion: 2022-06-01
• Status Verified: 2022-10
• Last Update Submitted: 2024-02-22
• Last Update Posted: 2024-02-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 55

Inclusion Criteria

• Generalized tooth wear
• A minimum of three posterior teeth (premolars and molars) per quadrant
• A maximum of one edentulous space in need for treatment, with a maximum span of one tooth-width

Exclusion Criteria

• ASA 4
• Edentulous space has a span exceeding 1 tooth-width, or more than one space
• Functional problems (mouth opening <5cm, Temporomandibular Dysfunction)
• Severe periodontitis
• Strong gag reflex

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
degree of dental wear in height	7 years	µm per year

Secondary Outcome Measures

Name	Time	Method
The use of index teeth	7 years	ICC correlation between ranking of patients according to whole dentition or index teeth

Trial Locations

Locations (1)

Radboud University Medical Center; 🇳🇱 Nijmegen, Gelderland, Netherlands