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Clinical Trials/CTRI/2025/08/093066
CTRI/2025/08/093066Not yet recruitingPhase 3 4

A prospective study on the effectiveness of natrum muriaticum in managing depressive disorder assesses using hamilton depression rating sacle-17

Post graduated research funded by sarada krishna homoeopathic medical college1 site in 1 country34 target enrollmentStarted: August 30, 2025Last updated:

Trial Snapshot

Phase
Phase 3 4
Status
Not yet recruiting
Sponsor
Enrollment
34
Locations
1
Primary Endpoint
Assessment is done for every 2 weeks medication and the cases is followed up period

Study Overview

Brief Summary

INTRODUCTION: Depressive disorder is one of the most prevalent mental health conditions worldwide, characterized by persistent sadness, loss of interest, and impaired daily functioning. According to the World Health Organization (WHO), depression is a leading cause of disability globally, significantly impacting individuals’ quality of life, productivity, and overall well-being.  Natrum muriaticum is frequently prescribed based on the principle of individualization, especially in cases presenting with classical depressive symptoms like grief, sadness, and emotional suppression. The Hamilton Depression Rating Scale - 17 (HAM-D-17) is a validated and widely used clinician-administered questionnaire that assesses the severity of depression. It provides a structured method to

objectively evaluate the effectiveness of interventions aimed at reducing depressive symptoms. PROCEDURE: Patients diagnosed with depressive disorder, as per the ICD-10 criteria, will be assessed using the HAM-D-17 scale. After detailed case taking, Natrum muriaticum will be prescribed based on symptom similarity. At each follow-up visit, the assessment will be repeated using the HAM-D-17 scale. OUTCOME : The effectiveness of Natrum muriaticum will be assessed based on improvement in the Depressive Disorder HAM-D - 17 Scale.

Study Design

Study Type
Interventional
Allocation
Na
Masking
None

Eligibility Criteria

Ages
18.00 Year(s) to 65.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • Patients diagnosed with depressive disorder according to ICD-10 criteria. Age group.
  • 18 to 65 years. Both genders.

Exclusion Criteria

  • Patients with severe mental illness, currently on antidepressants or other homoeopathic medicines.
  • Pregnant and lactation women Patients under other psychiatric medications.

Outcomes

Primary Outcomes

Assessment is done for every 2 weeks medication and the cases is followed up period

Time Frame: 6months

of 6 months

Time Frame: 6months

Secondary Outcomes

  • Assessment is done for every 2 weeks medication and the cases is followed up period(of 6 months)

Investigators

Sponsor
Post graduated research funded by sarada krishna homoeopathic medical college
Sponsor Class
Private medical college
Responsible Party
Principal Investigator
Principal Investigator

Vishnu Priya

Sarada krishna homoeopathic medical college

Study Sites (1)

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