The Effect of Supplementation With Species of Lactobacillus on Anthropometric Measurements, Body Composition, Appetite and Serum Lipid Profile in Overweight and Obese Adults
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 72
- 试验地点
- 1
- 主要终点
- weight change
研究概览
简要总结
The investigators aimed to study the effect of supplementation with species of Lactobacillus on anthropometric measurements, body composition, appetite and serum lipid profile in overweight and obese adults
详细描述
The Objective of This Study was Evaluating the Effect of supplementation with Species of Lactobacillus on anthropometric measurements include weight, waist and hip circumference , body composition include body fat and muscle percent, appetite measured by visual analogues scale and serum lipid profile in overweight and obese adults.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age 18-65 years
- •BMI more than 25 Kg/m2
排除标准
- •taking drugs that could affect weight change, including anti-diabetic drugs, lipid lowering drugs
- •endocrine,cardiovascular, thyroid, or chronic liver disease.
- •had received surgery to reduce weight
- •taking probiotics or antibiotics within one month
- •Pregnancy or lactation or menopause
- •A history of cancer
- •Heart disease - cardiovascular, pulmonary, renal and diabetes
- •A history of autoimmune disease
- •Taking certain medications such as blood pressure control, statins, insulin sensitivity enhancers
- •weight change over five percent within three months
- •change in activity or diet habit
研究组 & 干预措施
Species of Lactobacillus
2 capsule/day of Lactofem Containing Species of Lactobacillus
干预措施: Species of Lactobacillus (Dietary Supplement)
lactose
2 capsule/day Containing lactose
干预措施: lactose (Dietary Supplement)
结局指标
主要结局
weight change
时间窗: Change from Baseline in body weight at 12 weeks
次要结局
- Appetite(Baseline,4 weeks, 8 weeks, 12 weeks)
- Anthropometric Measurement WHR(Baseline,12 weeks)
- mid arm circumference Measurement(Baseline,12 weeks)
- defecation(Baseline,4 weeks, 8 weeks, 12 weeks)
- blood pressure(Baseline,12 weeks)
- Anthropometric Measurement BMI(Baseline,4 weeks, 8 weeks, 12 weeks)
- Anthropometric Measurement WC(Baseline,12 weeks)
- Anthropometric Measurement HC(Baseline,12 weeks)
- Serum Lipid Profile(Baseline,12 weeks)
- skinfold thickness(Baseline,12 weeks)
- body fat percent(Baseline,12 weeks)