Correction of Anisometropic Amblyopia in Children.

• Conditions: Amblyopia; Anisometropic Amblyopia; Anisometropia and Aniseikonia; Refractive Errors
• Interventions: Diagnostic Test: Axial length measurement in millimeter (mm) by optical biometry device; Diagnostic Test: Autorefractometer to measure the refractive error in both eyes.

• Registration Number: NCT05325021
• Lead Sponsor: Benha University

Brief Summary

Anisometropic amblyopia among children in school age may affects quality of life and educational progress of children.

Detailed Description

Correction of anisometropic amblyopia depends on type of refractive error and axial length of the eye.

In this study, we will asses the types of anisometropia found in children at school age and investigate possible ways for correction of this type of amblyopia.

Study Timeline

• Status Verified: 2022-04
• Study Start: 2022-04-02
• Study First Submitted: 2022-04-05
• Study First Submitted QC: 2022-04-05
• Last Update Submitted: 2022-04-05
• Study First Posted: 2022-04-13
• Last Update Posted: 2022-04-13
• Primary Completion: 2022-09-30
• Study Completion: 2022-09-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• Anisometropic amblyopia.
• Children at school age ranged from 4 to 12 years old.

Exclusion Criteria

• Emmetropia children.
• Children had undergone any intraocular surgeries.
• Other types of amblyopia.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Axial myopia	Autorefractometer to measure the refractive error in both eyes.	children have anisometropia due to axial myopia, axial length will be measured by optical biometry device in millimeter (mm).
Refractive hyperopia	Axial length measurement in millimeter (mm) by optical biometry device	children have anisometropia due to refractive hyperopia, axial length will be measured by optical biometry device in mm.
Axial myopia	Axial length measurement in millimeter (mm) by optical biometry device	children have anisometropia due to axial myopia, axial length will be measured by optical biometry device in millimeter (mm).
Refractive myopia	Axial length measurement in millimeter (mm) by optical biometry device	children have anisometropia due to refractive myopia, axial length will be measured by optical biometry device in mm.
Axial hyperopia	Axial length measurement in millimeter (mm) by optical biometry device	children have anisometropia due to axial hyperopia, axial length will be measured by optical biometry device in mm.
Axial hyperopia	Autorefractometer to measure the refractive error in both eyes.	children have anisometropia due to axial hyperopia, axial length will be measured by optical biometry device in mm.
Refractive myopia	Autorefractometer to measure the refractive error in both eyes.	children have anisometropia due to refractive myopia, axial length will be measured by optical biometry device in mm.
Refractive hyperopia	Autorefractometer to measure the refractive error in both eyes.	children have anisometropia due to refractive hyperopia, axial length will be measured by optical biometry device in mm.

Primary Outcome Measures

Name	Time	Method
Axial length of both eyes.	Immediately after optical biometry test for each eye.	Measurement of axial length of both eyes in millimeter (mm).

Secondary Outcome Measures

Name	Time	Method
Incidence of refractive errors in anisometropic amblyopia	Immediately after autorefractometer test for each eye.	Type of refractive error found in anisometropia measured by autorefractometer in diopter (D).

Trial Locations

Locations (1)

Ahmed Abdelshafy Tabl; 🇪🇬 Banhā, Benha, Egypt