The influence of glucose administration during surgery on the postoperative glucose metabolism in the patients undergoing elective gastrectomy
Not Applicable
- Conditions
- Malignant tumor of stomach
- Registration Number
- JPRN-UMIN000002710
- Lead Sponsor
- Dep. of Anesthesiology, School of Medicine, Showa Univ.
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Not provided
Exclusion Criteria
1. Patients with hypermagnesemia 2. Patients with hypothyroidism 3. Diabetic patients, patients with abnormal glucose tolerance, and the patients with such disease histories 4. Patients with severe heart diseases 5. Patients with severe kidney dysfunction 6. Patients with severe liver dysfunction 7. Others who are deemed unsuitable for inclusion in the study for any other reason based on the assessment by the investigator
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Postoperative glucose metabolism evaluated by the insulin resistance (HOMA-IR) calculated by the following equation: HOMA-IR= serum glucose level (mg/dL) x serum insulin level (microU/mL )/405 The values are measured in early morning of the day following the surgery.
- Secondary Outcome Measures
Name Time Method 1. Intraoperative glucose tolerance (serum glucose, insulin, and C-peptide) 2. Intraoperative protein metabolism (urinary 3-methyhistidine) 3. Intraoperative fat metabolism (serum free fatty acid and ketone bodies) The values are measured every 2 hours during the surgery.