Pain Processing and Pain Reporting in Patients With Alzheimer's Disease
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- University of Aarhus
- Enrollment
- 47
- Locations
- 1
- Primary Endpoint
- Numerical rating scale (NRS)
Study Overview
Brief Summary
The study investigates pain processing and pain reporting in patients with Alzheimers disease compared to healthy participants.
Employing a within-subject design, the study includes patients with Alzheimers disease and healthy participants that are exposed to thermal stimuli. During the test session the facial expressions of the participant are video recorded.
By repeating this on separate test days, the involvement of pain relief and pain increase is investigated.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 50 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Mild to moderate patients with Alzheimers disease (group 1)
- •Healthy participants ( group 2)
Exclusion Criteria
- •Chronic pain conditions
- •Other medical, psychiatric or neurological disorders
- •Use of pain-reliving medication 24 hours prior to testing
Outcomes
Primary Outcomes
Numerical rating scale (NRS)
Time Frame: Participants will be tested on three different days. The numerical rating scale will be applied after each thermal stimulus for each test session.
Acute pain assessed on numerical rating scale from 0 (no pain experience) to 10 (worst pain), examining pain intensity. The participant will provide a number on the scale which reflects their pain intensity.
Secondary Outcomes
- Pain Assessment in persons with Impaired Cognition (PAIC)(Participants will be video recorded on each of the three test days during testing.)