Deprescribing and Health-related Effects

Completed

• Conditions: Chronic Disease
• Interventions: Other: Medication review

• Registration Number: NCT05721534
• Lead Sponsor: Anne Estrup Olesen

Brief Summary

In a primary care settled quality improvement project aiming to deprescribe medication through a medication review intervention, we investigated how the implemented medication changes affected health-related outcomes in real-life patients.

Detailed Description

The project was approved by the Management in the Municipality of Frederikshavn. According to Danish legislation, no formal permission from the national or regional Committee on Health Research Ethics was required for this type of study, as patients were not treated inferior to usual care and no biological material was collected. It was conducted as a quality improvement project and informed consent was not required for the specific data collected. The study is in compliance with the General Data Protection Regulation and a part of North Denmark Region's record of processing activities (K2023-008).

Study Timeline

• Study Start: 2020-01-01
• Primary Completion: 2021-12-31
• Study Completion: 2022-12-31
• Status Verified: 2023-02
• Study First Submitted: 2023-02-01
• Study First Submitted QC: 2023-02-01
• Last Update Submitted: 2023-02-01
• Study First Posted: 2023-02-10
• Last Update Posted: 2023-02-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 87

Inclusion Criteria

• new residents and residents that had not yet attended a consultation focusing on pharmacological treatment in The Chronic Care Model.
• patients were invited for the consultation focusing on pharmacological treatment in the month of their birthday and, thereby, included randomly and consecutively throughout the study period.

Exclusion Criteria

• unable to collaborate on follow-up questionnaires

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Community-dwelling patients with chronic disease	Medication review	Patients were invited for the consultation focusing on pharmacological treatment in the month of their birthday and, thereby, included randomly and consecutively throughout the study period.
Care home residents	Medication review	The intervention was offered to new residents and residents that had not yet attended a consultation focusing on pharmacological treatment in The Chronic Care Model.

Primary Outcome Measures

Name	Time	Method
self-reported health status	4 months	(on a scale from 1 to 10)

Secondary Outcome Measures

Name	Time	Method
general condition	4 months	(rated on a 5-point Likert Scale)
functional level	4 months	rated on a 5-point Likert Scale

Trial Locations

Locations (1)

Aalborg University Hospital; 🇩🇰 Aalborg, Denmark