Skip to main content
Clinical Trials/NCT05678036
NCT05678036
Not yet recruiting
Not Applicable

Effects on Mortality and Clinical Course of a Patient's Choice Model for Opioid Maintenance Treatment for Opioid Dependence - Evaluation of a System Enabling a Large Expansion of Treatment Providers and Treatment Access

Region Skane1 site in 1 country2,500 target enrollmentStarted: January 31, 2023Last updated:

Overview

Phase
Not Applicable
Status
Not yet recruiting
Enrollment
2,500
Locations
1
Primary Endpoint
Hospitalization for substance use disorder treatment

Overview

Brief Summary

Opioid dependence, for example involving addiction to injected or inhaled heroin or similar compounds, is associated with high mortality, typically from opioid overdose, and causes major physical and mental health complications, social problems and crime. Opioid maintenance treatment (OMT) has proven effective in opioid dependence. In 2014, a patient's choice reform in Skåne county, Sweden, was introduced and led to a vast extension of OMT in the region, including a large number of treatment providers and high access to treatment. Still, opioid-related mortality in the region remains high. While patients' access to treatment has been increased, the content and nature of treatment in the present system has been questioned. The present system, which dramatically altered treatment conditions and access for OMT in this region, has never been formally evaluated in any large-scale study. This study aims to assess clinical course of patients receiving OMT before and during the patient choice reform system, and effects on the extent and nature of opioid-related mortality in the region.

Study Design

Study Type
Observational
Observational Model
Ecologic Or Community
Time Perspective
Retrospective

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Patients included in opioid maintenance treatment in Skåne region.

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Hospitalization for substance use disorder treatment

Time Frame: study inclusion through 2022

Hospitalization for substance use disorder treatment

Mortality

Time Frame: study inclusion through 2022

Mortality and cause of death

Secondary Outcomes

  • Mental health disorder(study inclusion through 2022)
  • Physical disorder(study inclusion through 2022)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Anders C Håkansson

Professor

Region Skane

Study Sites (1)

Loading locations...

Similar Trials