Effects on Mortality and Clinical Course of a Patient's Choice Model for Opioid Maintenance Treatment for Opioid Dependence - Evaluation of a System Enabling a Large Expansion of Treatment Providers and Treatment Access
Overview
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Region Skane
- Enrollment
- 2,500
- Locations
- 1
- Primary Endpoint
- Hospitalization for substance use disorder treatment
Overview
Brief Summary
Opioid dependence, for example involving addiction to injected or inhaled heroin or similar compounds, is associated with high mortality, typically from opioid overdose, and causes major physical and mental health complications, social problems and crime. Opioid maintenance treatment (OMT) has proven effective in opioid dependence. In 2014, a patient's choice reform in Skåne county, Sweden, was introduced and led to a vast extension of OMT in the region, including a large number of treatment providers and high access to treatment. Still, opioid-related mortality in the region remains high. While patients' access to treatment has been increased, the content and nature of treatment in the present system has been questioned. The present system, which dramatically altered treatment conditions and access for OMT in this region, has never been formally evaluated in any large-scale study. This study aims to assess clinical course of patients receiving OMT before and during the patient choice reform system, and effects on the extent and nature of opioid-related mortality in the region.
Study Design
- Study Type
- Observational
- Observational Model
- Ecologic Or Community
- Time Perspective
- Retrospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients included in opioid maintenance treatment in Skåne region.
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Hospitalization for substance use disorder treatment
Time Frame: study inclusion through 2022
Hospitalization for substance use disorder treatment
Mortality
Time Frame: study inclusion through 2022
Mortality and cause of death
Secondary Outcomes
- Mental health disorder(study inclusion through 2022)
- Physical disorder(study inclusion through 2022)
Investigators
Anders C Håkansson
Professor
Region Skane