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临床试验/NCT05678036
NCT05678036尚未招募不适用

Effects on Mortality and Clinical Course of a Patient's Choice Model for Opioid Maintenance Treatment for Opioid Dependence - Evaluation of a System Enabling a Large Expansion of Treatment Providers and Treatment Access

Region Skane1 个研究点 分布在 1 个国家目标入组 2,500 人开始时间: 2023年1月31日最近更新:
适应症
相关药物

试验速览

阶段
不适用
状态
尚未招募
发起方
Region Skane
入组人数
2,500
试验地点
1
主要终点
Hospitalization for substance use disorder treatment

研究概览

简要总结

Opioid dependence, for example involving addiction to injected or inhaled heroin or similar compounds, is associated with high mortality, typically from opioid overdose, and causes major physical and mental health complications, social problems and crime. Opioid maintenance treatment (OMT) has proven effective in opioid dependence. In 2014, a patient's choice reform in Skåne county, Sweden, was introduced and led to a vast extension of OMT in the region, including a large number of treatment providers and high access to treatment. Still, opioid-related mortality in the region remains high. While patients' access to treatment has been increased, the content and nature of treatment in the present system has been questioned. The present system, which dramatically altered treatment conditions and access for OMT in this region, has never been formally evaluated in any large-scale study. This study aims to assess clinical course of patients receiving OMT before and during the patient choice reform system, and effects on the extent and nature of opioid-related mortality in the region.

研究设计

研究类型
Observational
观察模型
Ecologic Or Community
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients included in opioid maintenance treatment in Skåne region.

排除标准

  • 未提供

结局指标

主要结局

Hospitalization for substance use disorder treatment

时间窗: study inclusion through 2022

Hospitalization for substance use disorder treatment

Mortality

时间窗: study inclusion through 2022

Mortality and cause of death

次要结局

  • Mental health disorder(study inclusion through 2022)
  • Physical disorder(study inclusion through 2022)

研究者

发起方
Region Skane
申办方类型
Other
责任方
Principal Investigator
主要研究者

Anders C Håkansson

Professor

Region Skane

研究点 (1)

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