Fascial Tissue Response to Manual Therapy: Implications in Long COVID-19

Not Applicable

Recruiting

• Conditions: COVID-19
• Interventions: Other: Guidebook; Other: Guidebook and Myofascial Reorganization® (RMF).

• Registration Number: NCT06348186
• Lead Sponsor: University of the State of Santa Catarina

Brief Summary

According to the World Health Organization (WHO), as of mid-September 2022, more than 21 million Brazilians have recovered from COVID-19. However, post-infection symptoms continue to appear months after the end of the acute infection, a syndrome called long COVID. Therefore, the aim of this study is to investigate the responses of fascia-focused manual therapy in participants with long COVID.

Detailed Description

Participants reported to have long COVID, of both sexes, aged between 20 and 80 years, from the community, outpatient clinics and hospitals will be evaluated. The treatment of participants will be carried out at the CEFID-UDESC Physiotherapy School Clinic, where they will undergo assessment of the biomechanical and viscoelastic properties of tissues, postural control, pain and quality of life. For normality analysis, the Shapiro-Wilk test will be applied, and according to the distribution of the data, parametric or non-parametric tests will be used. Pre- and post-assessment and treatment data will be compared using descriptive statistics and Student's t-test with a significance level of p=0.05 for parametric data or Wilcoxon for non-parametric data.

Study Timeline

• Study Start: 2024-02-01
• Primary Completion: 2024-04-01
• Study First Submitted: 2024-04-03
• Study First Submitted QC: 2024-04-03
• Study First Posted: 2024-04-04
• Status Verified: 2024-05
• Last Update Submitted: 2024-11-18
• Last Update Posted: 2024-11-20
• Study Completion: 2025-08-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Participants diagnosed with long COVID, of both sexes, aged between 20 and 80 years, from the community, outpatient clinics and hospitals.

Exclusion Criteria

• Participants with suspected deep vein thrombosis; Participants with neurological disorders.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Guidebook	Guidebook	-
Guidebook and Myofascial Reorganization® (RMF).	Guidebook and Myofascial Reorganization® (RMF).	-

Primary Outcome Measures

Name	Time	Method
Functioning and disability	6 weeks	Will be assessed using the "World Health Organization Disability Assessment" questionnaire (WHO-DAS 2.0), translated and validated for the Brazilian population by Silveira et al. (2013).
Biomechanical and tissue viscoelastic properties	6 weeks	Will be evaluated by MyotonPro (MytonPro, Myoton Ltd.s., Tartu, Estonia)

Secondary Outcome Measures

Name	Time	Method
Work capacity	6 weeks	Will be assessed by the "Work Limitations Questionnaire, WLQ-25" translated and validated for the Brazilian population by Soárez et al (2007).
Level of Quality of life	6 weeks	Will be assessed by the "World Health Organization Questionnaire" in its short version, validated in the Brazilian population and by the "Medical Outcomes Study 36-Item Short Form Health" questionnaire Survey" validated for Brazilian-Portuguese.
Upper limb dysfunctions	6 weeks	Will be assessed using the Arm, Shoulder and Hand Dysfunctions questionnaire (DASH), translated and validated for the Brazilian population by Orfale et al (2005).
Balance	6 weeks	Will be assessed using the Neurocom Balance Platform (VRS Sport) and its NeuroCom®Balance Manager program (Neurocom International, Inc, Clackamas, OR).

Trial Locations

Locations (1)

Santa Catarina State University; 🇧🇷 Florianópolis, Santa Catarina, Brazil