A randomised Open -Label Controlled Clinical Study to Evaluate The Efficacy of Masya Paayasa in the Management of Ksheen Shukra with special Reference to Oligospermia
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Subjective Parameters :
研究概览
简要总结
Infertility is defined as the failure of a couple to achieve a clinical pregnancy with regular unprotected sexual intercourse after 12 months or more. Low sperm count (oligospermia ) is one of the main causes of male infertility and is correlated with ksheena shukra . Dushti of shukravaha srotas , decreases the production of shukra dhatu leads to ksheena shukra. Ayurveda also explained in detail about infertility, its cause’s pathophysiology, and treatment under the umbrella of Vajikarana Aphrodisiac, one of the branches of Ayurveda. In Ayurveda various terms related to infertility are explained like Klaibya, Napunsaka, and Shanda which are indicative of impotency and the conditions like Shukra Dosha, Shukra Doshja Klaibya, Alparetasa, and Kshinaretasa can be related terms with infertility
NEED FOR STUDY**:**
Infertility is a problem of global proportion affecting an average of 8%–12% of couples worldwide .
Among the present data, also a male factor is solely liable for infertility in approximately 20% and contributory in another 30-40% of couples; intrinsically, a male factor is implicated in additional than 50% of couples seeking out for conception4
In present study one such formulation Masha paayasa(trial drug) has been mentioned by Acharaya ChakrapaniinChakraduttis taken to assess its efficacy in ksheenshukra w.s.r**to Oligospermia and compared with Vidarayadi**choorana(controlled drug) .
研究设计
- 研究类型
- Interventional
- 分配方式
- Other
- 盲法
- None
入排标准
- 年龄范围
- 25.00 Year(s) 至 45.00 Year(s)(—)
- 性别
- Male
入选标准
- •Inclusion criteria :- 1.Patients presenting with Pratyatma Lakshana of Kshina shukra ie.
- •Klaibyam, Shukra avisarga, Maithuna ashakti etc.with semen samples suggestive of Oligospermia.
- •Sperm count less than 15 million / ml .
- •3.Male patients of age ranging from 25 to 45 years.
排除标准
- •Exclusion criteria :- Age below 25 and above 45 years.
- •Patients with aspermia.
- •Genetic defects like Klinefelter syndrome.
- •Patients with diseases like Varicocele, Sexually transmitted diseases, and systemic diseases like DM, trauma, and any other chronic disorder etc.
结局指标
主要结局
Subjective Parameters :
时间窗: Baseline
Symptoms of Ksheena shukra :
时间窗: Baseline
Klaibyam, Shukra avisarga, Maithuna ashakti etc.
时间窗: Baseline
Sexual health parameters - Desire, Erection, Ejaculation and Orgasm will be graded and assessed.
时间窗: Baseline
Objective parameters :
时间窗: Baseline
Semen analysis.
时间窗: Baseline
次要结局
- 1.Seman Analysis(Baseline ,15th ,30th and 45th day)
研究者
Dr Sunil Kamboj
Jammu Institute of Ayurveda and Research,Jammu
