跳至主要内容
临床试验/CTRI/2025/02/080820
CTRI/2025/02/080820尚未招募3 期

A randomised Open -Label Controlled Clinical Study to Evaluate The Efficacy of Masya Paayasa in the Management of Ksheen Shukra with special Reference to Oligospermia

Jammu Institution of Ayurveda and Research ,Jammu1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2025年3月1日最近更新:

试验速览

阶段
3 期
状态
尚未招募
发起方
入组人数
30
试验地点
1
主要终点
Subjective Parameters :

研究概览

简要总结

Infertility is defined as the failure of a couple to achieve a clinical pregnancy with regular unprotected  sexual intercourse after 12 months or more. Low sperm count  (oligospermia ) is one of the main causes of male infertility and is correlated with  ksheena shukra .  Dushti of shukravaha srotas  , decreases the production of shukra dhatu leads to ksheena shukra. Ayurveda also explained in detail about infertility, its cause’s pathophysiology, and treatment under the umbrella of Vajikarana Aphrodisiac, one of the branches of Ayurveda. In Ayurveda various terms related to infertility are explained like Klaibya, Napunsaka, and Shanda which are indicative of impotency and the conditions like Shukra Dosha, Shukra Doshja Klaibya, Alparetasa, and Kshinaretasa can be related terms with infertility

NEED FOR STUDY**:**

Infertility is a problem of global proportion affecting an  average of 8%–12% of couples worldwide  .

Among the present data, also a male factor is solely liable  for infertility in approximately 20% and contributory in another 30-40% of couples; intrinsically, a male  factor is implicated in additional than 50% of couples seeking out for conception4

 In present study one such formulation Masha paayasa(trial drug) has been mentioned by  Acharaya ChakrapaniinChakraduttis taken to assess its efficacy in ksheenshukra w.s.r**to Oligospermia and compared with Vidarayadi**choorana(controlled drug)  .

研究设计

研究类型
Interventional
分配方式
Other
盲法
None

入排标准

年龄范围
25.00 Year(s) 至 45.00 Year(s)(—)
性别
Male

入选标准

  • Inclusion criteria :- 1.Patients presenting with Pratyatma Lakshana of Kshina shukra ie.
  • Klaibyam, Shukra avisarga, Maithuna ashakti etc.with semen samples suggestive of Oligospermia.
  • Sperm count less than 15 million / ml .
  • 3.Male patients of age ranging from 25 to 45 years.

排除标准

  • Exclusion criteria :- Age below 25 and above 45 years.
  • Patients with aspermia.
  • Genetic defects like Klinefelter syndrome.
  • Patients with diseases like Varicocele, Sexually transmitted diseases, and systemic diseases like DM, trauma, and any other chronic disorder etc.

结局指标

主要结局

Subjective Parameters :

时间窗: Baseline

Symptoms of Ksheena shukra :

时间窗: Baseline

Klaibyam, Shukra avisarga, Maithuna ashakti etc.

时间窗: Baseline

Sexual health parameters - Desire, Erection, Ejaculation and Orgasm will be graded and assessed.

时间窗: Baseline

Objective parameters :

时间窗: Baseline

Semen analysis.

时间窗: Baseline

次要结局

  • 1.Seman Analysis(Baseline ,15th ,30th and 45th day)

研究者

发起方
Jammu Institution of Ayurveda and Research ,Jammu
申办方类型
Other [private Ayurveda college]
责任方
Principal Investigator
主要研究者

Dr Sunil Kamboj

Jammu Institute of Ayurveda and Research,Jammu

研究点 (1)

Loading locations...

相似试验