The effect of Korean red ginseng on glucose metabolism and diabetic complications in type 2 diabetes mellitus

Not Applicable

Completed

• Conditions: Diabetes mellitus; Nutritional, Metabolic, Endocrine

• Registration Number: ISRCTN17039603
• Lead Sponsor: Korea Ginseng Corporation

Brief Summary

2020 Results article in https://doi.org/10.1155/2020/5295328 (added 11/10/2023)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2017-08-02
• Study Start: 2017-09-05
• Last Update Posted: 23 October 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 83

Inclusion Criteria

1. Men and women between 19 and 75 years of age with Type 2 diabetes on oral antidiabetic agents
2. Diagnosed with Type 2 diabetes more than 6 months ago
3. Unchanged dose or type of antidiabetic agents within the last 3 months

Exclusion Criteria

1. Patients with HbA1c>10%
2. Patients with eGFR < 30 mL/min/1.73 m2, AST/ALT > 3 times greater the upper normal limit
3. Taking glucocorticoid or any herbal medicine within the past 3 months
4. Chronic inflammatory disease in the active phase or acute infection status
5. Pregnant or lactating women

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Diabetic microvascular complication markers (estimated glomerular filtration rate (eGFR), urinary albumin to creatinine ratio (uACR), Kidney injury molecule-1 (KIM1), laminin-P1 as a marker for diabetic retinopathy, and current perception thresholds (CPT)), measured at week 24

Secondary Outcome Measures

Name	Time	Method
Fasting plasma glucose and HbA1c, measured by blood test at week 24