Chest CT Scan in Pulmonary Mucormycosis: Prognostic Value
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Death rate in patients with probable or proven invasive Mucorales infection
研究概览
简要总结
Invasive pulmonary fungal infections caused by Mucorales are rare but severe and rapidly progressive, affecting immunocompromised patients. The role of chest imaging in their diagnosis is well established in the 2020 EORTC/MSGERC criteria, and its use is almost systematic. However, the progression of lung parenchymal involvement and any potential prognostic radiological patterns in the follow-up of these infections are less well understood. This research aims to identify imaging characteristics predictive of favorable or unfavorable outcomes in infected patients, in order to better tailor follow-up and therapeutic options.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged 18 years or older
- •Treated at Strasbourg University Hospital between January 1, 2009, and June 3, 2025
- •With a diagnosis of probable or proven invasive pulmonary infection with Mucorales according to the 2020 EORTC/MSGERC criteria
- •Having undergone at least one CT scan including the thoracic region
排除标准
- •No CT scan including the thoracic region
- •No diagnosis of probable or proven invasive pulmonary infection with Mucorales (EORTC/MSGERC 2020 criteria)
结局指标
主要结局
Death rate in patients with probable or proven invasive Mucorales infection
时间窗: Day 15 after infection
Death rate at day 15 in patients with probable or proven invasive Mucorales infection
次要结局
未报告次要终点