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Clinical Trials/NCT05384600
NCT05384600
Completed
Not Applicable

Incisional Hernia Prevention: Risk-benefit From a Patient's Perspective

Cardiff and Vale University Health Board1 site in 1 country120 target enrollmentJune 17, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Incisional Hernia
Sponsor
Cardiff and Vale University Health Board
Enrollment
120
Locations
1
Primary Endpoint
Impact of incisional hernia risk scores on surgical mesh acceptibility
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

Incisional Hernia (IH) is a common complication of abdominal surgery and causes serious morbidity to patients. IH formation is multifactorial and its risk varies from patient to patient. Risk-predictive tools have been developed to identify patients at high risk of IH before their initial operation, with high-risk patients possibly being offered the use of prophylactic mesh, placed at the end of the operation to prevent IH from forming. With controversy surrounding the use of mesh in other types of surgery, however, it is not known if mesh use is acceptable to patients. This study aims to assess how patients feel about prophylactic mesh and whether it is acceptable to them.

Detailed Description

Incisional hernias are bulges through the abdominal wall that occur at the site of previous surgery. They are common, affecting between 12-20% of patients undergoing abdominal surgery, can pose a significant cost to the NHS and cause serious morbidity to patients. Risk-prediction tools are being developed with the aim of working out a person's risk of developing an incisional hernia before their operation. It is hoped that this will allow surgeons to give patients an idea of what their risk is before the operation happens so that patients can understand if they are at high, medium or low risk, and what they might be able to do about it before the operation. For patients that are "high risk" for developing an incisional hernia, it may be possible to use a synthetic mesh, similar to those used to fix groin hernias. This would be placed in the wound at the end of the initial operation to strengthen the wound to try and reduce the chance of developing an incisional hernia, however to date, no studies have looked at whether patients would find this acceptable. This study aims to establish whether mesh placed to prevent hernias during the initial surgery would be acceptable to patients. This, in turn, can be used to inform the design of future research studies surrounding the use of surgical mesh.

Registry
clinicaltrials.gov
Start Date
June 17, 2022
End Date
June 30, 2023
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Group 1 Patients who have previously undergone abdominal surgery, and subsequently developed incisional hernia.
  • Over the age of 18 years old
  • Able and willing to provide valid informed consent
  • Undergone elective or emergency colonic resection \>12 months ago
  • Clinical or radiological diagnosis of incisional hernia.
  • Where possible, patients will only be approached to participate where their clinical record indicates they are aware that they have a diagnosis of incisional hernia.
  • Group 2 Patients who have undergone abdominal surgery, but have not subsequently developed incisional hernia.
  • Over the age of 18 years old
  • Able and willing to provide valid informed consent
  • Undergone emergency abdominal surgery \> 12 months ago OR elective colonic resection \> 12 months ago

Exclusion Criteria

  • All participants (groups 1, 2 \& 3)
  • Unable or unwilling to give informed consent
  • Palliative diagnosis either at time of surgery, or since
  • Inability to understand or complete study questionnaires, due to intellectual or cognitive impairment or due to insufficient English-language skills

Outcomes

Primary Outcomes

Impact of incisional hernia risk scores on surgical mesh acceptibility

Time Frame: 12 months

A combination of qualitative and quantitative methods will explore how incisional hernia risk impacts perception of surgical mesh use Non-validated questionnaire developed based on Health Belief Model Theory, consisting of multiple 5-point Likert scale (min.1, max. 5), used in combination with semi-structured interviews to evaluate: A) Perception of risk in relation to incisional hernia B) Perception of personalised risk scoring C) Impact of A) and B) on surgical mesh use

Acceptability of prophylactic surgical mesh use to patients

Time Frame: 12 months

A combination of qualitative and quantitative methods will explore patient perceptions of prophylactic mesh. Non-validated questionnaire developed based on Health Belief Model Theory, consisting of multiple 5-point Likert scale (min.1, max. 5), used in combination with semi-structured interviews to evaluate: A) Understanding of surgical mesh B) Perceptions of surgical mesh risk C) Perceptions of surgical mesh benefit

Secondary Outcomes

  • Factors that modify acceptability of surgical mesh(9 months)
  • Patient understanding of Incisional Hernia(9 months)

Study Sites (1)

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