Early Discharge to Clinic-Based Therapy of Patients Presenting with Heart Failure (EDICT-HF Trial)

Not Applicable

Recruiting

• Conditions: heart failure; Cardiovascular - Other cardiovascular diseases; Public Health - Health service research

• Registration Number: ACTRN12624000002583
• Lead Sponsor: Dr Ben Costello

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2024-01-08
• Last Update Posted: 12 February 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 460

Inclusion Criteria

•Adult patients (>18 years) presenting to Sunshine Hospital / Footscray Hospital emergency department with ADHF
•Patients admitted to an inpatient ward at Sunshine Hospital / Footscray Hospital with ADHF for <48hrs
•Presentation of ADHF will be determined according to clinical presence of at least 1 relevant symptom and sign:
oSymptoms: Dyspnoea, orthopnoea, oedema
oSigns: Rales, peripheral oedema, ascites, pulmonary vascular congestion on chest radiography
•Raised B-Type Natriuretic Peptide (BNP) (>30 pmol/L)
•Informed consent is able to be received from participant

Exclusion Criteria

•Haemodynamic instability: Systolic blood pressure <90mmHg or >180mmHg or Heart Rate >100 bpm or <60bpm
•Raised oxygen requirements: Oxygen saturation < 93% on Room Air or Respiratory rate >24 breaths/min
•Serum creatinine >250 umol/L +/- estimated glomerular filtration rate <30 ml/min/1.73m2
•Elevated Serum C-Reactive Protein (CRP) >50 mg/L
•Intravenous vasodilatory or ionotropic agent requirement (excluding Digoxin)
•Febrile >38 degrees Celsius or clinical suspicion of infection
•Evidence of consolidation on chest radiography
•Inpatient admission >48hrs
•Meeting Fourth Universal Definition of Myocardial Infarction criteria
•Unstable arrhythmia (ventricular or supraventricular arrhythmia associated with haemodynamic instability or symptoms)
•Unsafe home discharge environment
•Social or language barriers limiting capacity to gain informed consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
30-day readmission rate[Measured as percentage of participants requiring at least one hospitalisation within 30 days<br>Assessment method: assessed by data linkage to medical records 30 days from discharge from active outpatient / inpatient care.]