A Prospective Assessment of the Perioperative Parameter and Treatment Outcomes of Surgical Treatment for Benign Prostate Hyperplasia in Hong Kong
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 2,000
- 试验地点
- 3
- 主要终点
- International Prostate Symptom Score (IPSS) questionnaire total Score
研究概览
简要总结
This is a prospective data registry to assess the treatment outcomes and complications of different treatment approaches in our hospital clusters.
详细描述
Benign prostatic hyperplasia (BPH) is a very common disease affecting men. Patients with BPH may present with voiding symptoms including hesitancy, intermittence, slow stream and sensation of incomplete emptying, and storage symptoms including urinary frequency, urgency and nocturia. Patients may also suffer from complications including urinary retention, recurrent urinary tract infection, bladder stone formation and obstructive uropathy. For patients who have lower urinary tract symptoms refractory to medications, or those who suffer from complications of BPH, transurethral prostatectomy should be considered.
Surgical intervention options have evolved from electrosurgical resection to the use of lasers for enucleation and ablation [1]. Aquablation and Rezum system are new minimally invasive surgical technology for BPH management. [2,3,4]. Different treatment approaches will result in different treatment successful rate and also potential adverse effects to patients.
However, large-scale studies investigating the different modalities of surgical treatment of BPH are lacking. Therefore, a prospective data registry is created to assess the perioperative surgical outcomes for different surgical treatment of BPH.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Patient at the age of 18 or above
排除标准
- •Patient is unable to give consent
结局指标
主要结局
International Prostate Symptom Score (IPSS) questionnaire total Score
时间窗: Baseline, 3 months after surgical treatment for BPH
Change in total scores in International Prostate Symptom Score (ranges from 0 to 35) questionnaires
Voiding function in uroflowmetry
时间窗: Baseline, 3 months after after surgical treatment for BPH
Change in urodynamic function assessed by Uroflowmetry
次要结局
- Complication after surgical treatment(Post operation 30 days after surgical treatment for BPH)
研究者
NG Chi Fai
Professor
Chinese University of Hong Kong
