The Effects of Phototherapy in Preterm Infants Pda
- Conditions
- Patent Ductus Arteriosus After Premature BirthHyper Bilirubinemia
- Registration Number
- NCT03675425
- Lead Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
- Brief Summary
The study was designed to assess whether chest shielding during phototherapy reduces the incidence of PDA, as assessed by serial echocardiographic examinations, in a population of extremely preterm infants born at lower 30 week gestation.
- Detailed Description
Phototherapy is a therapeutic intervention frequently used for management of neonatal hyperbilirubinaemia in extremely premature infants, especially in the first week when patency of the ductus is a clinical problem. Phototherapy has also been implicated in increased ductal patency. One randomized, controlled trial showed that chest shielding during phototherapy reduced the incidence and severity of PDA by 50% in preterm infants. These findings were mainly based on clinical evaluation of the ductus with echocardiographic studies performed only on a subgroup of infants noted to have a murmur on clinical examination.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 54
- Gestational week ≤ 30 weeks receiving phototherapy due to jaundice and infants who can perform echocardiography before and after treatment will be included in the study.
- Babies with congenital heart disease.
- Infants with major structural anomalies and infants who can not undergo echocardiography before or after treatment.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method echocardiographic examination first week presence of Patent Ductus arteriozus
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Zekai Tahir Burak Matarnity Teaching
🇹🇷Ankara, Turkey