Long-term Outcomes of Implants in Patients with Periodontitis

Completed

• Conditions: Peri-Implant Health; Peri-implant Mucositis; Periodontitis; Peri-implantitis

• Registration Number: NCT06852599
• Lead Sponsor: Heidelberg University

Brief Summary

The aim of the study is to examine potential influencing factors on the changes in the periodontal parameters probing pocket depth (PPD), bleeding on probing (BOP), and alveolar bone loss (ABL) on implants and control teeth (using a split-mouth design) over five (T-5), 7.5 (T-7), and ten years (T-10) of supportive periodontal care (SPC). For this purpose, 150 patients with periodontitis and implants are re-examined cross-sectionally (T0), and the changes in the main peri-implant and periodontal target parameters are compared retrospectively at the specified observation time points (T-5, T-7, T-10).

Potential influencing factors to peri-implant conditions include patient-related factors, therapy-related factors and implant-related factors. In addition, patients will be surveyed using validated questionnaires on oral health-related quality of life (OHIP-G14), and a number of common risk factors for periodontits and peri-implant conditions.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-09-01
• Primary Completion: 2024-05-30
• Study Completion: 2024-05-30
• Study First Submitted: 2025-02-24
• Study First Submitted QC: 2025-02-24
• Study First Posted: 2025-02-28
• Status Verified: 2025-03
• Last Update Submitted: 2025-03-03
• Last Update Posted: 2025-03-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

Patient-related:

• At least one dental implant present
• Age ≥ 18 years at the beginning of the observation period
• Verbal and written consent
• Complete periodontal and dental status at one of the defined observation time points with 6 probing sites per tooth/implant and bleeding on probing (BOP) recorded during the periodontal maintenance phase

Locally:

• a contralateral control tooth to the implant is present at the first defined observation time point
• BOP recorded on the implant

Exclusion Criteria

• No written and verbal consent
• Younger than 18 years

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
changes in periodontal pocket depths	over five, 7.5, and ten years of supportive periodontal care

Trial Locations

Locations (1)

Heidelberg University; 🇩🇪 Heidelberg, Baden-Württemberg, Germany