The Intervention Effect and Potential Neural Mechanisms of Music Therapy in Children and Adolescents With NSSI
Overview
- Phase
- N/A
- Intervention
- conventional treatment
- Conditions
- Mood Disorders in Children and Adolescents
- Sponsor
- Shanghai Mental Health Center
- Enrollment
- 54
- Locations
- 2
- Primary Endpoint
- psychological scale measurement：Screen for Child Anxiety Related Emotional Disorders (SCARED)
- Status
- Active, Not Recruiting
- Last Updated
- 4 days ago
Overview
Brief Summary
This study plans to combine questionnaires, scales, electrophysiological and neuroimaging methods to comprehensively evaluate the effectiveness of music therapy for children and adolescents with emotional disorders and NSSI, and explore the potential neural mechanisms of its effectiveness.
Detailed Description
The subjects will be randomly divided into the conventional treatment group (TAU) and the music therapy group (MT). The conventional treatment group will receive DBT group therapy 5 times a week, 1 hour each time, and individual personalized therapy twice a week; the music therapy group will receive individual music therapy twice a week, 30 minutes each time, for a total of 3 weeks on top of conventional treatment. During each intervention, near-infrared brain functional imaging, electrodermal and electrocardiographic equipment will be used to synchronously collect multimodal data from therapists and patients. The heart rate variability, electrodermal conductance response of therapists and patients, and the relative concentrations of oxygenated hemoglobin (oxy-Hb), deoxyhemoglobin (deoxy-Hb) and total hemoglobin in the brain tissue of the subjects and therapists were monitored during the treatment process.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Right-handed;
- •Born and raised in China, with Chinese as the only native language;
- •Voluntary participation, with the consent of the family members of patients under 18 years old, and signed the informed consent form;
- •Meet the diagnostic criteria of DSM-5 anxiety disorder or depressive disorder;
- •There have been two or more self-harm behaviors in the past six months.
Exclusion Criteria
- •Meet the diagnostic criteria of DSM-5 psychotic disorder, manic episode, autism spectrum disorder, mental retardation, tic disorder, substance abuse and other mental illnesses;
- •Severe organic brain disease;
- •Hearing loss or loss of music-related pleasure;
- •Those who have clear suicidal ideation, attempt and behavior in the past month.
Arms & Interventions
conventional treatment
The conventional treatment group receives DBT group therapy 5 times a week, each time for 1 hour, and also received individual personalized therapy twice a week.
Intervention: conventional treatment
conventional treatment plus music intervention
The music therapy group receives individual music therapy twice a week, 30 minutes each time, for a total of 3 weeks on top of conventional treatment.
Intervention: conventional treatment plus music intervention
Outcomes
Primary Outcomes
psychological scale measurement：Screen for Child Anxiety Related Emotional Disorders (SCARED)
Time Frame: before and after three weeks of music intervention
Before and after the entire music intervention course, Screen for Child Anxiety Related Emotional Disorders (SCARED) scale is administered to the subjects as baseline and final data. The minimum value is 0. The maximum value is 82. Higher scores means a worse result(the more anxious the person is). A total score of ≥ 25 may indicate the presence of an Anxiety Disorder. Scores higher than 30 are more specific.
psychological scale measurement：Beck Depression Inventory-II (BDI-II)
Time Frame: before and after three weeks of music intervention
Before and after the entire music intervention course, Beck Depression Inventory-II (BDI-II) scale is administered to the subjects as baseline and final data. This scale is used to assess the severity of depressive symptoms in the past two weeks, and contains 21 items, each item is scored on a level of 0\~3, and the total score of the scale is the sum of the scores of 21 items. According to the cut-off score provided by the original scale such as Beck, the total score of 0\~13 is no depression, 14\~19 is mild depression, 20\~28 is moderate depression, and 29\~63 is severe depression. The minimum value is 0. The maximum value is 63. Higher scores means a worse result.
psychological scale measurement：Beck Scale for Suicide Ideation (BSS)
Time Frame: before and after three weeks of music intervention
Before and after the entire music intervention courseBeck Scale for Suicide Ideation (BSS) scale is administered to the subjects as baseline and final data. There are 3 options for the scale answers, and the corresponding scores from left to right are 1, 2, and 3, with the higher the score, the stronger the desire to die. All visitors complete the first 5 questions first, and if the answer to the 4th and 5th items is "no", then they are considered to have no suicidal ideation and complete this questionnaire; If any one of the 4th or 5th items is "weak" or "moderate to strong", then it is considered suicidal ideation and you need to continue to complete the next 14 items. The higher the score, the greater the intensity of suicidal ideation. Higher scores means a worse result.
Secondary Outcomes
- psychological scale measurement：Children's Depression Inventory (CDI)(before and after three weeks of music intervention)
- psychological scale measurement：Fear of Negative Evaluation Scale (FNE)(before and after three weeks of music intervention)
- psychological scale measurement：Emotion Regulation Questionnaire (ERQ)(before and after three weeks of music intervention)
- psychological scale measurement：Alexian Brothers Urge to Self-Injure Scale (ABUSI)(before and after three weeks of music intervention)
- psychological scale measurement：Difficulties in Emotion Regulation Scale (DERS)(before and after three weeks of music intervention)
- psychological scale measurement：Center for Epidemiologic Studies Depression Scale (CES-D)(before and after three weeks of music intervention)
- DBT-Ways of Coping Checklist (DBT-WCCL)(before and after three weeks of music intervention)