EUCTR2014-001541-24-DE
Active, not recruiting
Phase 1
euroenhancement of Interpersonal Psychotherapy in Major Depression
niversity Medical Center Freiburg0 sitesAugust 4, 2015
ConditionsMajor Depression (ICD-10F32.2/F33.2)Therapeutic area: Psychiatry and Psychology [F] - Mental Disorders [F03]
DrugsCycloserine
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Major Depression (ICD-10
- Sponsor
- niversity Medical Center Freiburg
- Status
- Active, not recruiting
- Last Updated
- 9 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Major depressive disorder (ICD\-10: F32\.2 and F33\.2\)
- •Inpatients at the Department of Psychiatry and Psychotherapy, Freiburg
- •Score of \=15 on the 21\-item Hamilton Rating Scale for Depression (HAMD)
- •20\-60 years of age
- •Ability to provide informed consent
- •Normal or corrected\-to\-normal vision
- •Absence of any exclusion criteria
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1\.2 Adults (18\-64 years) yes
Exclusion Criteria
- •Hypersensitivity to D\-cycloserine
- •Neurological disorders including epilepsy, history of brain injury, encephalitis, or any organic brain syndrome
- •Metallic implants
- •Present pregnancy
- •DSM\-V axis I disorder (lifetime) apart from major depression, such as schizophrenia, schizoaffective disorder, any non\-bipolar psychotic disorder, bipolar disorders, primary anxiety or obsessive compulsive disorder, mental retardation, signs of impaired cognitive functioning
- •Acute suicidality
- •Psychotic features of MDD
- •Lifetime history for drug/alcohol dependence, or drug/alcohol abuse within the past year
- •Medication with any anxiolytic or antipsychotic drug, except antidepressants for patients
- •Medical conditions including severe cardiac, liver, kidney, endocrine (e.g., diabetes), hematologic disorders (e.g., porphyria or any bleeding abnormalities), other impairing or unstable medical condition or impending surgery
Outcomes
Primary Outcomes
Not specified
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