Limitation of the Ventilatory Response to Exercise in the Master Athlete: Influences on Locomotor Muscle Fatigue and on Endurance Performance
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 3
- 试验地点
- 1
- 主要终点
- Change from baseline severity of EFL during ergocycle endurance exercise
研究概览
简要总结
It is generally accepted that the ventilatory system is not a limiting factor in physical exercise in terms of performance or exercise tolerance in healthy subjects. The ventilatory system would be oversized in relation to the stresses it has to cope with, even during maximum intensity exercise. However, some highly trained endurance athletes may be exceptions to this rule. A limitation of the expiratory flow is indeed sometimes found in these athletes, whose maximum values of ventilation can confront the mechanical limits of their ventilatory system. This phenomenon could be accentuated in elderly athletes (known as "master athletes") under the effect of structural and functional pulmonary alterations that accompany aging. Our hypothesis : What is the prevalence of exercise expiratory flow limitation in the master athlete and does it cause a decrease in physical performance via an acceleration of locomotor muscle fatigue?
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Non-smoker (active or passive) or ex-smoker of less than 5 pack-years and stopped for more than 10 years.
- •No known significant chronic pathology.
- •No symptoms suggesting a progressive pathology.
- •No contraindication to physical exercise. Normal Pulmonary Functional Test (PFT).
- •Participants affiliated to the social security system
排除标准
- •Vulnerable persons as defined in Articles L. 1121-5 to L.1121-8 and L.1122-1-2 of the Public Health Code (e.g. persons deprived of liberty, minors, adults protected, etc.),
- •Participants with a medical contraindication to sports practice,
- •Cardiovascular, respiratory, neuromuscular and/or significant metabolic,
- •Participants with declared pathology or medical treatment,
- •Smoking or drug use,
- •Significant chronic drug treatment,
- •Lack of consent.
- •Refusal to cooperate
- •Recent rhino-bronchial infection (within last 4 weeks)
- •Mental disability
研究组 & 干预措施
Healthy volunteers
Following the selection visit (#V0) to verify the inclusion and non-inclusion criteria, participants will make 2 visits (#V1 and #V2) including in particular a Respiratory Functional Exploration (EFR) and a triangular
干预措施: Air (Other)
Healthy volunteers
Following the selection visit (#V0) to verify the inclusion and non-inclusion criteria, participants will make 2 visits (#V1 and #V2) including in particular a Respiratory Functional Exploration (EFR) and a triangular
干预措施: Heliox (Other)
结局指标
主要结局
Change from baseline severity of EFL during ergocycle endurance exercise
时间窗: At inclusion and 3 months
Force developed by the quadriceps muscle in response to percutaneous electrical stimulation of the femoral nerve
次要结局
- Muscle activation level(At inclusion and 3 months)