Evaluation of Mineral Trioxide Aggregates and Grape Seeds Extract Effect on Pulpotomy

Not Applicable

Completed

• Conditions: Dental Caries

• Registration Number: NCT06694064
• Lead Sponsor: Al-Azhar University

Brief Summary

Pediatric dentistry has always debated the benefits of vital pulp therapy. AIM: The current study was done to differentiate the histo-pathological findings of MTA versus grape seed extract in primary teeth undergoing pulpotomy as pulp dressing substances. Materials and Methods: According to the inclusion criteria, 16 primary teeth were selected in each group. Randomly and equally, the teeth were split into two groups: (MTA group) Group I, and (GSE group) Group II. After nine months, under a light microscope the teeth were evaluated and a clinical follow-up was conducted. Periapical radiographs were also taken at this time.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-01-02
• Primary Completion: 2024-01-10
• Study Completion: 2024-09-02
• Study First Submitted: 2024-10-21
• Status Verified: 2024-11
• Study First Submitted QC: 2024-11-16
• Last Update Submitted: 2024-11-16
• Study First Posted: 2024-11-19
• Last Update Posted: 2024-11-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 16

Inclusion Criteria

• healthy patients with carious primary molars

Exclusion Criteria

• root resorption

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
evaluate pain of the teeth	6 months	The lack of any clinical indications of pulp degeneration, such as the history of spontaneous pain, pain on percussion, swelling, pathological mobility, or sinus tract

Secondary Outcome Measures

Name	Time	Method
absence of radiolucency	6 months	No signs of periapical orfurcal radiolucency, widening of the periodontal ligament (PDL), or pathological root resorption (internal or external).

Trial Locations

Locations (1)

Alazhar University; 🇪🇬 Cairo, Egypt