Varicocelectomy: Can Sex-hormones Predict Improvements in Semen Quality?
Not Applicable
Terminated
- Conditions
- VaricoceleInfertilitySemen Quality
- Interventions
- Procedure: Hormone and semen measurements before varicocelectomy
- Registration Number
- NCT01296230
- Lead Sponsor
- Copenhagen University Hospital at Herlev
- Brief Summary
The purpose of this study is to determine if the pre-operative levels of sex-hormones can be used to identify the varicocele patients who can expect improvements in their semen parameters following varicocelectomy.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- Male
- Target Recruitment
- 3
Inclusion Criteria
- Varicocele (grade 1-3) and surgery planned for this condition
- At least 18 years of age
Exclusion Criteria
- Fever within 3 months before the first semen sample
- Malformations of the uro-genital tract
- Karyotype other than 46, XY or Y micro deletions
- Endocrine disease
- Chronic disease
- Medications which reduce semen quality
- Epididymitis within 6 months before surgery
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Hormone/semen measurements before and after varicocelectomy Hormone and semen measurements before varicocelectomy We will measure sex-hormone and semen quality in patients both before and after varicocelectomy. The purpose is to asses if preoperative hormone levels are predictive for who will have improved semen quality after surgery.
- Primary Outcome Measures
Name Time Method Change in semen parameters February 2017 (anticipated duration of the study)
- Secondary Outcome Measures
Name Time Method Change in hormone levels February 2017 (anticipated end of the study)
Trial Locations
- Locations (2)
Department of Urology, Herlev Hospital
🇩🇰Herlev, Denmark
University Department of Growth and Reproduction GR, Section 5064, Rigshospitalet
🇩🇰Copenhagen, Denmark