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Clinical Trials/NCT01659333
NCT01659333
Completed
Not Applicable

Volume Status in Peritoneal Dialysis Patients With Using Different Determining Methods.

TC Erciyes University1 site in 1 country60 target enrollmentJanuary 2011

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Disorders Associated With Peritoneal Dialysis
Sponsor
TC Erciyes University
Enrollment
60
Locations
1
Primary Endpoint
Terminated of patients recruiting
Status
Completed
Last Updated
13 years ago

Overview

Brief Summary

Dry weight (DW) assessment is essential for the efficient treatment of peritoneal dialysis (PD) patients but so far objective methods for DW assessment have not been established for daily clinical practice. Our aim was to evaluate hydration state in PD patients by using a body composition monitor (BCM) and calf bioimpedance (c-BI) and N-terminal prohormone of brain natriuretic peptide (NT-proBNP) levels and to compare both methods with arterial stiffness.

Detailed Description

We evaluated 60 patients using a new BCM device that implies a validated body composition model. This method allows correct quantification of extracellular fluid overload or deficiency (normal limits:-1.1 to +1.1L). Patients were assigned to normo and hypervolemic groups according to BCM results. Also, normalized calf resistivity (nRho) was calculated from resistance at 5 Khz using c-BI and the levels of NT-proBNP were measured in all study patients. The analyses of arterial stiffness were performed by using the pulse wave velocity (PWV) technique on the patients. All patients underwent conventional echocardiography and their left ventricular diastolic functions were evaluated.

Registry
clinicaltrials.gov
Start Date
January 2011
End Date
February 2012
Last Updated
13 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Ismail Kocyigit

Associate Professor

TC Erciyes University

Eligibility Criteria

Inclusion Criteria

  • Peritoneal dialysis patients
  • All participants over 18 years of age

Exclusion Criteria

  • Patients with valvular heart disease
  • Patients with coronary artery disease
  • Patients with cardiomyopathy
  • Patients with ESRD who underwent hemodialysis

Outcomes

Primary Outcomes

Terminated of patients recruiting

Time Frame: One year

Study Sites (1)

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