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Effect of Ambient Noise on the Responses to Meal Ingestion

Not Applicable
Completed
Conditions
Healthy
Registration Number
NCT03827707
Lead Sponsor
Hospital Universitari Vall d'Hebron Research Institute
Brief Summary

Meal ingestion induces sensations that are influenced by a series of conditioning factors. Aim: to determine the effect of ambient noise on the sensory responses to a standard probe meal. Randomized, cross-over study in healthy subjects comparing the effect of ambient noise versus silence on the sensations induced by a probe meal. Participants (12 men) will be instructed to eat a standard dinner the day before, to consume a standard breakfast at home after overnight fast, and to report to the laboratory, where the test meal will be administered 5 h after breakfast. Studies will be conducted in a quiet, isolated room with participants sitting on a chair. One study day, a noise will applied via headphones for 60 min after meal ingestion and the other day headphones without sound will applied. Perception of homeostatic sensations (hunger/ satiation, fullness) and hedonic sensations (digestive well-being, mood) will be measured at 5 min intervals 10 min before and 20 min after ingestion and at 10 min intervals up to 60 min after the probe meal.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
Male
Target Recruitment
12
Inclusion Criteria
  • non-obese
Exclusion Criteria
  • history of gastrointestinal symptoms
  • prior obesity
  • use of medications
  • history of anosmia and ageusia
  • current dieting
  • alcohol abuse
  • psychological disorders
  • eating disorders

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Primary Outcome Measures
NameTimeMethod
Change in digestive well-being induced by the probe meal1 day

Effect of noise on digestive well-being \[measured by a 10 cm scale graded from -5 (extremely unpleasant sensation) to +5 (extremely pleasant sensation)\] by repeated measures ANCOVA (dependent variable: postprandial sensations scores; within subject's factors: noise and time; covariate: premeal scores).

Secondary Outcome Measures
NameTimeMethod
Change in fullness sensation induced by the probe meal1 day

Effect of noise on fullness \[measured by a 10 cm scale graded from 0 (not at all) to 10 (very much)\] by repeated measures ANCOVA (dependent variable: postprandial sensations scores; within subject's factors: noise and time; covariate: premeal scores).

Change in hunger/satiety induced by the probe meal1 day

Effect of noise on hunger/satiety \[measured by a 10 cm scale graded from -5 (extremely hungry) to +5 (completely satiate)\] by repeated measures ANCOVA (dependent variable: postprandial sensations scores; within subject's factors: noise and time; covariate: premeal scores).

Change in mood induced by the probe meal1 day

Effect of noise on mood \[measured by a 10 cm scale graded from -5 (negative) to +5 (positive)\] by repeated measures ANCOVA (dependent variable: postprandial sensations scores; within subject's factors: noise and time; covariate: premeal scores).

Trial Locations

Locations (1)

University Hospital Vall d'Hebron

🇪🇸

Barcelona, Spain

University Hospital Vall d'Hebron
🇪🇸Barcelona, Spain
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