Factors That Determine the Responses to Meal Ingestion: Effect of Ambient Noise
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Healthy
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
- Enrollment
- 12
- Locations
- 1
- Primary Endpoint
- Change in digestive well-being induced by the probe meal
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
Meal ingestion induces sensations that are influenced by a series of conditioning factors. Aim: to determine the effect of ambient noise on the sensory responses to a standard probe meal. Randomized, cross-over study in healthy subjects comparing the effect of ambient noise versus silence on the sensations induced by a probe meal. Participants (12 men) will be instructed to eat a standard dinner the day before, to consume a standard breakfast at home after overnight fast, and to report to the laboratory, where the test meal will be administered 5 h after breakfast. Studies will be conducted in a quiet, isolated room with participants sitting on a chair. One study day, a noise will applied via headphones for 60 min after meal ingestion and the other day headphones without sound will applied. Perception of homeostatic sensations (hunger/ satiation, fullness) and hedonic sensations (digestive well-being, mood) will be measured at 5 min intervals 10 min before and 20 min after ingestion and at 10 min intervals up to 60 min after the probe meal.
Investigators
Eligibility Criteria
Inclusion Criteria
- •non-obese
Exclusion Criteria
- •history of gastrointestinal symptoms
- •prior obesity
- •use of medications
- •history of anosmia and ageusia
- •current dieting
- •alcohol abuse
- •psychological disorders
- •eating disorders
Outcomes
Primary Outcomes
Change in digestive well-being induced by the probe meal
Time Frame: 1 day
Effect of noise on digestive well-being \[measured by a 10 cm scale graded from -5 (extremely unpleasant sensation) to +5 (extremely pleasant sensation)\] by repeated measures ANCOVA (dependent variable: postprandial sensations scores; within subject's factors: noise and time; covariate: premeal scores).
Secondary Outcomes
- Change in fullness sensation induced by the probe meal(1 day)
- Change in hunger/satiety induced by the probe meal(1 day)
- Change in mood induced by the probe meal(1 day)