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Clinical Trials/CTRI/2025/12/098796
CTRI/2025/12/098796Not yet recruitingNot Applicable

Impact of Resistance training on Blood Glucose levels, Gestational Weight Gain, Quality of Life and Fatigue in Females diagnosed with Gestational Diabetes Mellitus

Poorvi mathur1 site in 1 country40 target enrollmentStarted: December 20, 2025Last updated:

Trial Snapshot

Phase
Not Applicable
Status
Not yet recruiting
Sponsor
Enrollment
40
Locations
1

Study Overview

Brief Summary

Gestational diabetes is brought on by additional hormones released during pregnancy that can reduce the effectiveness of insulin, a condition known as insulin resistance, GDM is diagnosed in the second or third trimester of pregnancy. Placental hormones, such as human placental lactogen and placental growth hormone, cause a progressive development of insulin resistance in mother to provide the fetus with the adequate amount of glucose, Maternal hyperglycemia during pregnancy has deleterious at all stages of fetal development, increased risk of malformations. In the fetus, maternal diabetes leads to high birth weight and increased fat mass, including asphyxia, obstetrical trauma, respiratory distress and hypoglycemia. Exercise has its insulin sensitising effects by increasing sensitivity GLUT-4 to insulin and increased glycogen synthase, an increase in muscle mass through resistance training is associated with improved glycemic control, Resistance training influences blood glucose level, weight gain, QOL and fatigue in women diagnosed with gestational diabetes.

Inclusion Criteria- those diagnosed with GDM, age between 18 and 35years; gestational age between 14 and 34 weeks  Exclusion Criteria- participation in other planned and supervised exercise programs or research activity during this research period (2) patients with severe obstetric contraindications and complications, patients with multiple foetus, History of previous pre-term delivery. 

Participants will be selected from the Obstetrics and Gynecology Outpatient Department (OPD), The treatment protocol will consist of 30 minutes of exercise per day, 5 days a week, for a period of 4 weeks,Group A (Experimental): Participants will receive resistance training exercises to be performed on 5 days per week.

Group B (Control): Participants will follow the instructions provided by their gynecologist for controlling GDM. Pre intervention data will be collected on recruitment in study and

at the end of the 4th week, post-intervention measurements of the outcome variables will be taken.

Study Design

Study Type
Interventional
Allocation
Coin toss, Lottery, toss of dice, shuffling cards etc
Masking
Participant Blinded

Eligibility Criteria

Ages
18.00 Year(s) to 35.00 Year(s) (—)
Sex
Female

Inclusion Criteria

  • (1) those diagnosed with GDM, (2) age between 18 and 35years; (3) gestational age between 14 and 34 weeks (4) BMI-18.5-24.9kg/m2 (5) SF-12 questionnaire score for PCS below 50 and MCS score below 42.

Exclusion Criteria

  • (1) participation in other planned and supervised exercise programs or research activity during this research period (2) patients with severe obstetric contraindications and complications (3) patients with multiple foetus.
  • (4) History of previous pre-term delivery.

Investigators

Sponsor
Poorvi mathur
Sponsor Class
Private medical college
Responsible Party
Principal Investigator
Principal Investigator

Poorvi Mathur

SGT University

Study Sites (1)

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