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临床试验/CTRI/2025/12/098796
CTRI/2025/12/098796尚未招募不适用

Impact of Resistance training on Blood Glucose levels, Gestational Weight Gain, Quality of Life and Fatigue in Females diagnosed with Gestational Diabetes Mellitus

Poorvi mathur1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2025年12月20日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
40
试验地点
1

研究概览

简要总结

Gestational diabetes is brought on by additional hormones released during pregnancy that can reduce the effectiveness of insulin, a condition known as insulin resistance, GDM is diagnosed in the second or third trimester of pregnancy. Placental hormones, such as human placental lactogen and placental growth hormone, cause a progressive development of insulin resistance in mother to provide the fetus with the adequate amount of glucose, Maternal hyperglycemia during pregnancy has deleterious at all stages of fetal development, increased risk of malformations. In the fetus, maternal diabetes leads to high birth weight and increased fat mass, including asphyxia, obstetrical trauma, respiratory distress and hypoglycemia. Exercise has its insulin sensitising effects by increasing sensitivity GLUT-4 to insulin and increased glycogen synthase, an increase in muscle mass through resistance training is associated with improved glycemic control, Resistance training influences blood glucose level, weight gain, QOL and fatigue in women diagnosed with gestational diabetes.

Inclusion Criteria- those diagnosed with GDM, age between 18 and 35years; gestational age between 14 and 34 weeks  Exclusion Criteria- participation in other planned and supervised exercise programs or research activity during this research period (2) patients with severe obstetric contraindications and complications, patients with multiple foetus, History of previous pre-term delivery. 

Participants will be selected from the Obstetrics and Gynecology Outpatient Department (OPD), The treatment protocol will consist of 30 minutes of exercise per day, 5 days a week, for a period of 4 weeks,Group A (Experimental): Participants will receive resistance training exercises to be performed on 5 days per week.

Group B (Control): Participants will follow the instructions provided by their gynecologist for controlling GDM. Pre intervention data will be collected on recruitment in study and

at the end of the 4th week, post-intervention measurements of the outcome variables will be taken.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
Participant Blinded

入排标准

年龄范围
18.00 Year(s) 至 35.00 Year(s)(—)
性别
Female

入选标准

  • (1) those diagnosed with GDM, (2) age between 18 and 35years; (3) gestational age between 14 and 34 weeks (4) BMI-18.5-24.9kg/m2 (5) SF-12 questionnaire score for PCS below 50 and MCS score below 42.

排除标准

  • (1) participation in other planned and supervised exercise programs or research activity during this research period (2) patients with severe obstetric contraindications and complications (3) patients with multiple foetus.
  • (4) History of previous pre-term delivery.

研究者

发起方
Poorvi mathur
申办方类型
Private medical college
责任方
Principal Investigator
主要研究者

Poorvi Mathur

SGT University

研究点 (1)

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