Evaluation of the Effects of Treatment With Bioarginin C in Adult Subjects Belonging to the Post-Covid Day Hospital

Not Applicable

• Conditions: Inflammation; Fatigue Syndrome, Chronic
• Interventions: Dietary Supplement: Bioarginina C

• Registration Number: NCT04947488
• Lead Sponsor: University of Milan

Brief Summary

Long Covid could be much more frequent than it is thought to be. Few dwell on the great problem represented by the post covid syndrome. The virus often leaves important marks on our body, and those who recover face problems of various kinds: chronic fatigue, shortness of breath, dry cough, headache, cognitive difficulties.

On the duration and resolution of this syndrome, now recognized as a highly debilitating condition, there are still no great answers: for this reason it is always important to emphasize that contracting Covid, even in a not serious form, still means exposing oneself to long-term risks that are still not well codified by the scientific community. Guidelines and more tools are expected to best assist these patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-06-18
• Study First Submitted: 2021-06-30
• Study First Submitted QC: 2021-06-30
• Study First Posted: 2021-07-01
• Status Verified: 2022-05
• Last Update Submitted: 2022-05-16
• Last Update Posted: 2022-05-17
• Primary Completion: 2022-09-18
• Study Completion: 2022-11-18

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

subjects with proven positivity to the molecular test for Sars-cov2 with demonstration of microbiological healing patients discharged from FPG or other hospital structures; or only contact in PS; or home management age: range 20-60 years Fatigue operationalized as an affirmative answer to item "7" (CES-D)

Exclusion Criteria

Pharmacological therapies with possible interactions with the mechanisms / processes under study (e.g. antihypertensive drugs, cortisone drugs, NSAIDs, immunosuppressants, nitrates)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Bioarginina C	Bioarginina C	vials based on L-arginine and liposomal vitamin C
Placebo	Bioarginina C	vials without L-arginine and liposomal vitamin C

Primary Outcome Measures

Name	Time	Method
6 minute walking test to evaluate Fatigue	30 days	Effect of Bioarginina C on the prolonged fatigue

Trial Locations

Locations (1)

Barbara Maglione; 🇮🇹 Napoli, Italy