The Effect of Air Pollution on Lung Health Among Children Living in Haifa Bay Region, Israel

Not Applicable

Completed

• Conditions: Bronchial Asthma; Signs and Symptoms, Respiratory; Allergy
• Interventions: Device: Spirometry (Pony spirometer)

• Registration Number: NCT00718133
• Lead Sponsor: Carmel Medical Center

Brief Summary

Haifa bay region is located close to a major industrial zone. The aim of the study is to evaluate the health status of children living in Haifa bay region.

The health status will be evaluated using health questionnaires and spirometry.

Detailed Description

Haifa bay is located close to a major industrial zone. The aim of the study is to evaluate the health status of children living in Haifa bay region.

The health status will be evaluated while using health questionnaires and spirometry.

Objective: To evaluate the respiratory health of Haifa bay region children with comparatives, with respect to local air pollution levels.

Material and Methods: Children from Haifa bay region from 10 different communities (1200 children) will be included in the study, after both parents and the children (above 12 years of age) will sign an informed consent form.

First step: A health questionnaire (based on Hebrew version of ISAAC questionnaire) will be filled in by the parents.

Second step: Spirometry checking of the children. In parallel, air pollution levels will be measured and provided by a network of ground monitoring stations maintained by the Haifa District Municipality Association for the Environment (HDMAE). The station provides half-hourly measurement of mean concentrations of gaseous (NOX, SO2, O3) and particular (PM 10) pollutants over the entire investigation window. Additional meteorological data are also collected.

Risk maps: Using a GIS platform, we are developing a multi-layer risk mapping procedure which accounts for ambient concentrations of selected pollutants and the heterogenic spatial distribution of several demographic and socio-economic indexes in the region.

The prevalence of pulmonary disease will be evaluated according to the risk maps The health status of the children will be documented from the children's primary clinic files as well.

Study Timeline

• Study First Submitted: 2008-07-17
• Study First Submitted QC: 2008-07-17
• Study First Posted: 2008-07-18
• Study Start: 2008-12
• Primary Completion: 2009-08
• Status Verified: 2010-09
• Study Completion: 2010-09
• Last Update Submitted: 2010-09-13
• Last Update Posted: 2010-09-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

• Living in Haifa bay region, Israel.
• Parents signed informed consent.

Exclusion Criteria

• Children that their parents did not signed the informed consent
• Chronic disease except of asthma: Diabetes mellitus, Cystic Fibrosis, Cardiac diseases, Renal, Rheumatic and Chronic Gastrointestinal diseases, Mental retardation.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
1	Spirometry (Pony spirometer)	Children at school age from Haifa bay region

Primary Outcome Measures

Name	Time	Method
The prevalence of respiratory symptoms in respect to air pollution	Two years

Trial Locations

Locations (1)

Pediatric Center Armon Clinic; 🇮🇱 Haifa, Israel