跳至主要内容
临床试验/CTRI/2025/11/097113
CTRI/2025/11/097113尚未招募不适用

Assessment Of Periodontal Health Status in Patients Having Hypertension With and Without Smoking: An Observational Study With and Without Smoking An Observational Study

Ranjeet Deshmukh Dental College and Research Centre Nagpur1 个研究点 分布在 1 个国家目标入组 150 人开始时间: 2025年11月30日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
150
试验地点
1
主要终点
Their Oral Health assessments will be taken in which detailed periodontal examinations by trained dental professionals to measure Probing Pocket Depth, Clinical Attachment Level, Plaque Index & Gingival Index and Cardiovascular data in which Medical History collection & Blood Pressure measurements will be taken

研究概览

简要总结

Hypertension is a powerful independent contributor to cardiovascular morbidity and mortality, on average conferring a threefold increase in risk at all ages and in both sexes Changes in clinical, biochemical and pathological variables characterize cardiovascular damage from smoking and hypertension when it acts independently. Smoking increases the risks of vascular damage by increasing sympathetic tone, platelet stickiness and reactivity, free radical production, damage to endothelium, and by surges in arterial pressure. Active smoking is a widely accepted risk factor for cardiovascular disease and is recognized as a major public health problem. Passive smoking, also known as Second-Hand Smoke Exposure (SHSE), is thought to have similar cardiovascular consequences and the risk has been postulated to be equivalent to that of active smoking. Smoking has a dose-dependent effect on periodontium. Poor periodontal health is associated with increased prevalence of hypertension and may have an influence on BP control. Risk factors such as older age, male gender, non-Caucasian ethnicity, smoking, overweight/obesity, diabetes, low socioeconomic status, and poor education have been considered the common denominators underpinning this relationship.

研究设计

研究类型
Observational

入排标准

年龄范围
25.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Known cases of Hypertension Patients having more than 20 functional teeth.

排除标准

  • Patients suffering from any other systemic diseases except for Hypertension, allergies or drug usage Pregnant and Lactating women Subjects who have undergone periodontal therapy in last 6 months.

结局指标

主要结局

Their Oral Health assessments will be taken in which detailed periodontal examinations by trained dental professionals to measure Probing Pocket Depth, Clinical Attachment Level, Plaque Index & Gingival Index and Cardiovascular data in which Medical History collection & Blood Pressure measurements will be taken

时间窗: Baseline

次要结局

未报告次要终点

研究者

发起方
Ranjeet Deshmukh Dental College and Research Centre Nagpur
申办方类型
Other [Private Dental College]
责任方
Principal Investigator
主要研究者

Dr Puniti Bohria

Ranjeet Deshmukh Dental College and Research Centre, Nagpur

研究点 (1)

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