Investigating the Tolerability and Feasibility of tVNS Following aSAH
Not Applicable
Recruiting
- Conditions
- Subarachnoid Haemorrhage From Cerebral Aneurism Rupture
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Inclusion Criteria:<br><br> - Age >18<br><br> - Admitted to STH (Sheffield Teaching Hospital) neurosurgery department<br><br> - Confirmed aneurysmal SAH on vascular imaging<br><br> - Within 5 days of 'Securing' aneurysm (i.e., successfully coiled or surgically<br> following rupture)<br><br>Exclusion Criteria:<br><br> - Current or prior use of a vagus nerve stimulation<br><br> - Symptomatic bradycardia or PPM insertion<br><br> - Complete heart block<br><br> - Implantation of any other electrical stimulator (e.g. DBS)
Exclusion Criteria
Not provided
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Monitor tolerability for tVNS;Assess study feasibility
- Secondary Outcome Measures
Name Time Method Monitor safety criteria for tVNS;Rates of delayed cerebral ischaemia (DCI);Inpatient mortality;Length of inpatient stay;Rates of inpatient complications;Modified rankin score;Barthel Index;Inflammatory markers;Headache scores;Cerebral functional near-infrared spectroscopy;Heart rate variability;Pupillary light reactivity