To evaluate the effect of osseodensification technique on bone density around dental implants.

Recruiting

Conditions: Partial loss of teeth,

Registration Number: CTRI/2023/02/049512

Lead Sponsor: Bhujbal Rushikesh Bhau

Brief Summary: **Introduction**

Dental implant is the part of the prosthesisthat interfaces the bone and supportsthe dental prosthesis. It is a widely used treatment modality.

Primary stability in dental implants is anessential factor for achieving successful osseointegration. Surgical procedureand bone quality are among the most common factors that affect primarystability. It is also crucial to achieve high-insertion torque which isimportant for obtaining primary stability. Maintaining sufficient bone bulk anddensity is essential to achieve necessary bone-to-implant contact for obtaininga biomechanically stable implant. A new concept for osteotomy calledosseodensification (OD) has been at the forefront of changes in surgical sitepreparation in implantology.It is done with specially designedbur that has many lands with a large negative rake angle, which works asnoncutting edges to increase the density of the bone as they expand anosteotomy.

The bone density corresponds to the boneremodelling activity of osteoblast and osteoclast. Local factors like levels ofosteoprotegrin(OPG) has a significant role in it.

OPG is expressed by osteoblast.

The OPG protein is a novel member of TNFfamily.It is a regulator of bone density that act locally and systematically bynegatively regulating osteoclast maturation.

Its expression is regulated by most ofthe factors that induce RANKL expression by osteoblasts. OPG protects the skeleton from excessive bone resorption bybinding to RANKL and preventing it from binding to its receptor, RANK.

The aim of the present study is to comparatively evaluatethe effect of osseodensification technique on bone mineral density.

**RESEARCH HYPOTHESIS:**

*Null Hypothesis*

It will behypothesized that thereis no significant change in bone mineral density and osteoprotegrin arounddental implants placed through conventional drilling protocol with osseodensificationand conventional drilling protocol.

**Objective :**

1)To compare osteoprotegrinlevel in Periimplant crevicularfluid(PICF) from dental implants placed with osseodensification andconventional technique.

2) To compare bone mineral densityaround implants placed with osseodensification and conventional technique.

3) To find association betweenosteoprotegrin and bone mineral density.

Thistrial is in accordance with theConsolidated Standards of Reporting Trails(CONSORT) criteria, 2010.

Detailed Description: Not available

Recruitment & Eligibility

Status: Open to Recruitment

Sex: All

Target Recruitment: 48

Inclusion Criteria

1)Partial Edentulism in Maxilla.
2)Adequate Oral hygiene.
3)Adequate bone volume for implant placement.

Exclusion Criteria

1)Systemic Diseases.
2)Habit of smoking and chewing tobacco.
3)Bruxism 4)Bone diseases.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare osteoprotegrin level in periimplant crevicular fluid(PICF) from dental implants placed with osseodensification and conventional technique.	1)2 weeks \| 2)12 weeks

Secondary Outcome Measures

Name	Time	Method
To compare bone mineral density around dental implants placed with osseodensification and conventional technique.	1)Pre-operative(Baseline)
To find association between osteoprotegrin and bone mineral density.	1)2 weeks

Trial Locations

Locations (1): King Georges Medical University
🇮🇳
Lucknow, UTTAR PRADESH, India
King Georges Medical University
🇮🇳Lucknow, UTTAR PRADESH, India
Dr Bhujbal Rushikesh Bhau
Principal investigator
9096060601
dr.rushibhujbal@gmail.com