Mean arterial pressure alarm compared to hypotension prediction index in preventing intraoperative hypotensio

• Conditions: Intra-operative Hypotension; Intraoperative hypotension; Low blood pressure

• Registration Number: NL-OMON53215
• Lead Sponsor: Medisch Spectrum Twente

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 9 April 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

- Informed consent
- Aged 18 years or older
- Planned for moderate- or high-risk elective non-cardiac surgery under general
anaesthesia
- Need for continues blood pressure monitoring with the help of an arterial
line during surgery
- Target MAP of 65 mmHg during surgery
- Elective surgery

Exclusion Criteria

- Target MAP higher or lower than 65 mmHg
- Current persistent cardiac arrhythmias, including atrial fibrillation
- Liver and vascular surgery with vascular clamping
- Hypotension before surgery, defined as MAP<65mmHg
- Patients requiring dialysis
- Severe aortic valve stenosis
- Known clinically important cardiac shunts
- Congestive heart failure

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary outcome measure is the area under the threshold (AUT) of<br /><br>hypotension (defined as MAP<65 mmHg for at least one minute) during surgery. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- Incidence of hypotension<br /><br>- Time spend in hypotension<br /><br>- Length of hypotensive episodes<br /><br>- Time weighted average of hypotension<br /><br><br /><br>- Cross-correlation between MAP values and HPI values<br /><br><br /><br>- Troponin level before and after surgery<br /><br>- Creatine level before and after surgery<br /><br>- 30-day mortality after surgery </p><br>