Diagnostic Accuracy of Serum Bilirubin in the Prediction of Perforated Appendicitis

Completed

• Conditions: Appendicitis

• Registration Number: NCT01698099
• Lead Sponsor: University Hospital Tuebingen

Brief Summary

Hyperbilirubinemia is reported to be a positive predictor in diagnosing perforated appendicitis. Therefore we analysed the diagnostic accuracy of serum bilirubin in discriminating between perforated and simple/no appendicitis.

Methods:

All consecutive patients undergoing appendectomy for suspected appendicitis from May 2009 to August 2011 were analysed. Primary endpoint was the diagnostic accuracy of serum bilirubin levels to detect perforated appendicitis.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-05
• Primary Completion: 2011-08
• Status Verified: 2012-09
• Study Completion: 2012-09
• Study First Submitted: 2012-09-24
• Study First Submitted QC: 2012-09-27
• Last Update Submitted: 2012-09-27
• Study First Posted: 2012-10-02
• Last Update Posted: 2012-10-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 500

Inclusion Criteria

• all patients undergoing appendectomy for suspected appendicitis

Exclusion Criteria

• preexisting liver disease

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Diagnostic accuracy of serum bilirubin	24h within initial presentation with clinical symptoms	assessment of the diagnostic accuracy of hyperbilirubinemia (defined as serum bilirubin above 1.1 md/dl)

Trial Locations

Locations (1)

Departement of Visceral- and Transplant Surgery, University of Tuebingen; 🇩🇪 Tuebingen, Germany