NCT00004457Unknown不适用

Determinants of Disease Severity in Amyotrophic Lateral Sclerosis

National Institute of Neurological Disorders and Stroke (NINDS)0 个研究点目标入组 75 人开始时间: 1998年3月最近更新: 2005年6月24日

研究概览

简要总结

OBJECTIVES:

I. Determine specific clinical features, molecular abnormalities, and laboratory-based biological markers of free radical stress that are associated with amyotrophic lateral sclerosis and influence disease severity.

详细描述

PROTOCOL OUTLINE: This is a screening and diagnostic study. Blood and urine samples are collected from patients every 2 months for 1 year. All samples are evaluated for measures of free radical damage and levels of the body's own antioxidant activity.

研究设计

研究类型: Observational
观察模型: Defined Population
时间视角: Prospective

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

未提供

排除标准

未提供

研究者

发起方

National Institute of Neurological Disorders and Stroke (NINDS)

申办方类型

Nih

相似试验

已完成

不适用

Understanding Clinical Phenotype and Collecting Biomarker Samples in C9ORF72 ALSC9ORF72 Amyotrophic Lateral Sclerosis (ALS)

NCT02686268Washington University School of Medicine128

Unknown

不适用

Epidemiology and Genetics of the Amyotrophic Lateral Sclerosis in the French West IndiesAmyotrophic Lateral Sclerosis

NCT03367650Centre Hospitalier Universitaire de Pointe-a-Pitre70

进行中（未招募）

不适用

Phenotype, Genotype and Biomarkers 2Amyotrophic Lateral SclerosisHereditary Spastic ParaplegiaPrimary Lateral SclerosisProgressive Muscular AtrophyFrontotemporal Dementia

NCT04875416University of Miami217

尚未招募

Unknown

Exploratory study for diagnosis of amyotrophic lateral screrosis by metabolome analysisamyotrophic lateral sclerosis

JPRN-UMIN000051302niversity of Tsukuba20

招募中

不适用

Identification of the new biomarkers of amyotrophic lateral sclerosisAmyotrophic lateral sclerosis

JPRN-UMIN000013111agoya University Graduate school of Medicine60