Virtual Left Ventricular Lead Navigation in Patients With Ischemic Cardiomyopathy
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Cardiomyopathy
- Sponsor
- University of Pittsburgh
- Locations
- 1
- Primary Endpoint
- dP/dt measurements observed during pacing from different left ventricular regions
- Status
- Withdrawn
- Last Updated
- 10 years ago
Overview
Brief Summary
Presently, the left ventricular lead is placed in a similar position for all patients. It is not known whether placing this lead in different positions in the heart will make the heart pump better. In this study, the investigator will collect measurements of the heart's electrical activity during an Electrophysiology Study (EP study or EPS). The hope is that these measurements will provide the know how to develop an individualized left ventricular lead placement "prescription" for patients referred for left ventricular lead pacing.
Investigators
David Schwartzman
Professor of Medicine, Cardiac Electrophysiology, University of Pittsburgh
University of Pittsburgh
Eligibility Criteria
Inclusion Criteria
- •Ischemic cardiomyopathy
- •Intrinsic QRS duration \>120 milliseconds
- •LV ejection fraction \<40%
Exclusion Criteria
- •Persistent atrial tachyarrhythmia
- •Active cardiac ischemia
- •Cerebrovascular accident within 6 months
- •Surgical or percutaneous cardiac revascularization procedure within 3 months
- •Under 18 years of age
- •Participating in a clinical study that would preclude enrollment
- •Unable to provide informed consent
Outcomes
Primary Outcomes
dP/dt measurements observed during pacing from different left ventricular regions
Time Frame: Measurements will be observed at the time of the electrophysiology study (EPS) at enrollment.
During the electrophysiology study, the dP/dt measurements will be observed during pacing from different left ventricular regions.