Virtual LV Lead Navigation in Patients With Ischemic Cardiomyopathy

Not Applicable

Withdrawn

• Conditions: Cardiomyopathy; Ischemic Cardiomyopathy
• Interventions: Other: Collection of measurements during LV pacing during electrophysiology study

• Registration Number: NCT01825239
• Lead Sponsor: University of Pittsburgh

Brief Summary

Presently, the left ventricular lead is placed in a similar position for all patients. It is not known whether placing this lead in different positions in the heart will make the heart pump better. In this study, the investigator will collect measurements of the heart's electrical activity during an Electrophysiology Study (EP study or EPS). The hope is that these measurements will provide the know how to develop an individualized left ventricular lead placement "prescription" for patients referred for left ventricular lead pacing.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2013-04-02
• Study First Submitted QC: 2013-04-02
• Study First Posted: 2013-04-05
• Study Start: 2014-04
• Primary Completion: 2014-10
• Study Completion: 2014-10
• Status Verified: 2015-08
• Last Update Submitted: 2015-08-05
• Last Update Posted: 2015-08-07

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Ischemic cardiomyopathy
• Intrinsic QRS duration >120 milliseconds
• LV ejection fraction <40%

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Exclusion Criteria

• Persistent atrial tachyarrhythmia
• Active cardiac ischemia
• Cerebrovascular accident within 6 months
• Surgical or percutaneous cardiac revascularization procedure within 3 months
• Under 18 years of age
• Pregnant
• Participating in a clinical study that would preclude enrollment
• Unable to provide informed consent

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Electrophysiology Study	Collection of measurements during LV pacing during electrophysiology study	This is a single arm study, all study participants will be referred for an Electrophysiology Study

Primary Outcome Measures

Name	Time	Method
dP/dt measurements observed during pacing from different left ventricular regions	Measurements will be observed at the time of the electrophysiology study (EPS) at enrollment.	During the electrophysiology study, the dP/dt measurements will be observed during pacing from different left ventricular regions.

Trial Locations

Locations (1)

UPMC Presbyterian Hospital; 🇺🇸 Pittsburgh, Pennsylvania, United States