Mass Spectral Fingerprinting in Obstructive Sleep Apnoea

Completed

• Conditions: Exhaled Breath; Obstructive Sleep Apnoea (OSA); Mass Spectrometry

• Registration Number: NCT02810158
• Lead Sponsor: University of Zurich

Brief Summary

To answer the question whether a previously detected breath profile in patients suffering from obstructive sleep apnoea (OSA) can be found in a cohort of patients with suspected OSA using mass spectrometry (validation study).

Detailed Description

Not available

Study Timeline

• Study Start: 2016-06
• Study First Submitted: 2016-06-20
• Study First Submitted QC: 2016-06-20
• Study First Posted: 2016-06-22
• Primary Completion: 2018-05
• Study Completion: 2018-05
• Status Verified: 2018-10
• Last Update Submitted: 2018-10-18
• Last Update Posted: 2018-10-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

• Clinical suspicion of obstructive sleep apnoea syndrome (based on clinical symptoms such as increased daytime sleepiness; Epworth Sleepiness Score (ESS) > 10).
• Age between 18 and 85 years at study entry.

Exclusion Criteria

• None

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
OSA-specific mass spectrometric pattern of VOCs in the exhaled breath	one hour, single measurement, no follow-up	Concentration of volatile organic compounds (VOCs) in the exhaled breath will be analysed using mass spectrometry

Trial Locations

Locations (1)

University Hospital Zurich, Division of Pneumology; 🇨🇭 Zurich, ZH, Switzerland