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临床试验/NCT02881892
NCT02881892已完成不适用

Interleukin-6, Procalcitonin and Vascular Endothelial Growth Factor in Plasma and Dialysate Correlate With Peritoneal Solute Transport and Dialysis Adequacy in CAPD Patients

Bangkok Metropolitan Administration Medical College and Vajira Hospital1 个研究点 分布在 1 个国家目标入组 26 人开始时间: 2012年3月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
26
试验地点
1
主要终点
plasma level of VEGF, IL-6 and procalcitonin with the PSTR and dialysis adequacy in CAPD patients

研究概览

简要总结

The aim of study was to evaluated the correlation between plasma levels, dialysate appearance rate of VEGF, inflammatory cytokines (IL- 6, procalcitonin) and PSTR, dialysis adequacy in CAPD patients.

详细描述

This cross -sectional study measured IL-6, procalcitonin and VEGF level in plasma and overnight effluent. PSTR of small solutes was evaluated by standard peritoneal equilibration test (standard PET). Weekly Kt/V and creatinine clearance (CCr ) were evaluated in all patients.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Stable CAPD patients without previous history of peritonitis

排除标准

  • Other infections, tuberculosis or on immunosuppressive drugs,
  • Autoimmune disease,
  • Diagnosis of permanent ultrafiltration failure .

结局指标

主要结局

plasma level of VEGF, IL-6 and procalcitonin with the PSTR and dialysis adequacy in CAPD patients

时间窗: 2 years

measure in pg/ml

次要结局

  • Cytokines in diabetic and non-diabetic group(2 years)

研究者

申办方类型
Other Gov
责任方
Principal Investigator
主要研究者

Thananda Trakarnvanich

Associate Professor

Bangkok Metropolitan Administration Medical College and Vajira Hospital

研究点 (1)

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