Treatment of Fatigue in Multiple Sclerosis: Aerobic Training, Cognitive Behavioural Therapy, Energy Conservation Management
Completed
- Conditions
- fatiguemultiple sclerosis1001230320 gezonde proefpersonen tbv extra onderzoek beweegedrag
- Registration Number
- NL-OMON39391
- Lead Sponsor
- Vrije Universiteit Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 290
Inclusion Criteria
- Diagnosis of MS according to the criteria of McDonald
- an Expanded Disability Status Scale score of 6 or lower, i.e. able to walk without walking aid,
- suffering from fatigue, defined as a score higher than 35 on the subscale fatigue of the Checklist Individual Strength (CIS)
- In the last three months prior to inclusion the patients should not have used Amantadine, Modafinil, Ritalin or Pemoline for their fatigue.
- Age between 18-70 years
Exclusion Criteria
Treatable causes of fatigue. other than central MS-related fatigue
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Fatigue: Checklist Individual Strength (CIS) subscale fatigue<br /><br>Participation: Impact on Participation and Autonomy (IPA)<br /><br>Disease Activity: Number of exacerbations < 1 yr</p><br>
- Secondary Outcome Measures
Name Time Method