The Use of Immersive Virtual Reality for Upper Limb Neurorehabilitation in Stroke Survivors
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Chronic Stroke
- Sponsor
- Mindmaze SA
- Enrollment
- 10
- Locations
- 1
- Primary Endpoint
- Rehabilitation dose: goal-directed movements (i.e. number of intended movements to achieve a task)
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
The present study aims at investigating (i) the feasibility in chronic stroke of using a dedicated virtual reality (VR) based system that embeds real-time 3D motion capture and embodied visual feedback to deliver functional exercises designed for training of impaired upper limb motor skills, (ii) whether chronic stroke survivors improve in functional outcomes in the upper limb when exposed to intensive VR-based therapy, and (iii) safety and tolerance to such a technology. The investigators hypothesize that intensive VR-based rehabilitation may lead to high rehabilitation doses and functional improvement in chronic stroke.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Ischemic or hemorrhagic minor-to-moderate (0\<NIHSS\<16) stroke with hemiparesis and experiencing arm motor difficulties
- •At least 6 months after stroke incident
- •Maximum 4 on the Medical Research Council Scale (MRCS) for shoulder elevation and elbow flexion/extension
- •18 years and older
- •First ever stroke
Exclusion Criteria
- •Participating in another movement treatment study at the time of the present study
- •Severe cognitive impairment (Mini Mental Status Examination score \< 18 points)
- •Orthopedic impairment or visual disorders limiting the treatment
- •Unable to give informed consent form
- •Risk of epileptic seizures
Outcomes
Primary Outcomes
Rehabilitation dose: goal-directed movements (i.e. number of intended movements to achieve a task)
Time Frame: 5 weeks
Rehabilitation dose: goal-directed movements (i.e. number of intended movements to achieve a task)
Training intensity: number of goal-directed movements per minute of effective training time.
Time Frame: 5 weeks
Training intensity: number of goal-directed movements per minute of effective training time.
Change in Upper limb function assessed with Fugl-Meyer Assessment for Upper Extremity (FMA-UE)
Time Frame: At baseline, 5 weeks (post intervention) and 9 weeks (follow-up)
Fugl-Meyer Assessment for Upper Extremity (FMA-UE)
Secondary Outcomes
- Change in Modified Medical Research Council Scale (mMRCS)(At baseline, 5 weeks (post intervention) and 9 weeks (follow-up))
- Change in Functional Independence Measure (FIM)(At baseline, 5 weeks (post intervention) and 9 weeks (follow-up))
- Change in Visual Analog Scale (VAS) for Pain(At baseline, 5 weeks (post intervention) and 9 weeks (follow-up))
- Change in kinematic metrics/goniometry (active range of motion).(At baseline, 5 weeks (post intervention) and 9 weeks (follow-up))
- Safety and Acceptance of Technology assessed with a questionnaire(5 weeks)